Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma

Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The patatin-like phospholipase-3 (PNPLA3) I148M sequence variant is one of the strongest genetic determinants of NAFLD/NASH. PNPLA3 is an in...

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Detalles Bibliográficos
Autores principales: Kanda, Tatsuo, Goto, Taichiro, Hirotsu, Yosuke, Masuzaki, Ryota, Moriyama, Mitsuhiko, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073210/
https://www.ncbi.nlm.nih.gov/pubmed/32102237
http://dx.doi.org/10.3390/ijms21041525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073210/
https://www.ncbi.nlm.nih.gov/pubmed/32102237
http://dx.doi.org/10.3390/ijms21041525

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