Overcoming Resistance to FLT3 Inhibitors in the Treatment of FLT3-Mutated AML

Acute myeloid leukaemia (AML) carrying internal tandem duplication (ITD) of Fms-Like Tyrosine kinase 3 (FLT3) gene is associated with high risk of relapse and poor clinical outcome upon treatment with conventional chemotherapy. FLT3 inhibitors have been approved for the treatment of this AML subtype...

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Detalles Bibliográficos
Autores principales: Lam, Stephen S.Y., Leung, Anskar Y.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073218/
https://www.ncbi.nlm.nih.gov/pubmed/32102366
http://dx.doi.org/10.3390/ijms21041537

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