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Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer

Carcinogenesis is linked with massive changes in regulation of gene networks. We used high throughput mutation and gene expression data to interrogate involvement of 278 signaling, 72 metabolic, 48 DNA repair and 47 cytoskeleton molecular pathways in cancer. Totally, we analyzed 4910 primary tumor s...

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Detalles Bibliográficos
Autores principales:	Zolotovskaia, Marianna A., Tkachev, Victor S., Seryakov, Alexander P., Kuzmin, Denis V., Kamashev, Dmitry E., Sorokin, Maxim I., Roumiantsev, Sergey A., Buzdin, Anton A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073226/ https://www.ncbi.nlm.nih.gov/pubmed/31979117 http://dx.doi.org/10.3390/cancers12020271

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