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Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus?
OBJECTIVE: Gestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis of GDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatory indices and the risk of GDM occurrence using the complete blood c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073359/ https://www.ncbi.nlm.nih.gov/pubmed/32206652 http://dx.doi.org/10.5468/ogs.2020.63.2.133 |
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author | Fashami, Mahta Abbasi Hajian, Sepideh Afrakhteh, Maryam Khoob, Mehdi Khabaz |
author_facet | Fashami, Mahta Abbasi Hajian, Sepideh Afrakhteh, Maryam Khoob, Mehdi Khabaz |
author_sort | Fashami, Mahta Abbasi |
collection | PubMed |
description | OBJECTIVE: Gestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis of GDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatory indices and the risk of GDM occurrence using the complete blood count (CBC) test. We also aimed to determine the sensitivity of each parameter for an early screening of this disorder during pregnancy. METHODS: This case-control study included 2 groups of 110 pregnant women with and without GDM. The women in each group were compared after the routine screening for GDM and after the CBC test at 24–28 weeks' gestation after being matched according to the inclusion criteria. Data were analyzed using SPSS version 16 and Medcalc version 14.8.1 software. RESULTS: There were statistically significant intergroup differences in white blood cell (WBC) count, platelet count, mean platelet volume (MPV), plateletcrit (PCT), MPV to platelet ratio, platelet to lymphocyte ratio, and Rh values. The values of lymphocyte count, neutrophil count, neutrophil to lymphocyte ratio, and blood group were not significantly different between groups. The logistic regression analysis showed the predictive values of WBC, platelet, MPV, and PCT in GDM. According to the receiver operating characteristic curve for all 3 variables, the level below the PCT chart was more than that of the others. CONCLUSION: Increasing platelet and inflammatory indices on the CBC test in the second trimester of pregnancy seemed to be associated with the probability of GDM occurrence. |
format | Online Article Text |
id | pubmed-7073359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-70733592020-03-23 Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? Fashami, Mahta Abbasi Hajian, Sepideh Afrakhteh, Maryam Khoob, Mehdi Khabaz Obstet Gynecol Sci Original Article OBJECTIVE: Gestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis of GDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatory indices and the risk of GDM occurrence using the complete blood count (CBC) test. We also aimed to determine the sensitivity of each parameter for an early screening of this disorder during pregnancy. METHODS: This case-control study included 2 groups of 110 pregnant women with and without GDM. The women in each group were compared after the routine screening for GDM and after the CBC test at 24–28 weeks' gestation after being matched according to the inclusion criteria. Data were analyzed using SPSS version 16 and Medcalc version 14.8.1 software. RESULTS: There were statistically significant intergroup differences in white blood cell (WBC) count, platelet count, mean platelet volume (MPV), plateletcrit (PCT), MPV to platelet ratio, platelet to lymphocyte ratio, and Rh values. The values of lymphocyte count, neutrophil count, neutrophil to lymphocyte ratio, and blood group were not significantly different between groups. The logistic regression analysis showed the predictive values of WBC, platelet, MPV, and PCT in GDM. According to the receiver operating characteristic curve for all 3 variables, the level below the PCT chart was more than that of the others. CONCLUSION: Increasing platelet and inflammatory indices on the CBC test in the second trimester of pregnancy seemed to be associated with the probability of GDM occurrence. Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2020-03 2020-02-24 /pmc/articles/PMC7073359/ /pubmed/32206652 http://dx.doi.org/10.5468/ogs.2020.63.2.133 Text en Copyright © 2020 Korean Society of Obstetrics and Gynecology http://creativecommons.org/licenses/by-nc/3.0/ Articles published in Obstet Gynecol Sci are open-access, distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Fashami, Mahta Abbasi Hajian, Sepideh Afrakhteh, Maryam Khoob, Mehdi Khabaz Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title | Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title_full | Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title_fullStr | Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title_full_unstemmed | Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title_short | Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
title_sort | is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073359/ https://www.ncbi.nlm.nih.gov/pubmed/32206652 http://dx.doi.org/10.5468/ogs.2020.63.2.133 |
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