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Novel Alternatively Spliced Variants of Smad4 Expressed in TGF-β-Induced EMT Regulating Proliferation and Migration of A549 Cells

INTRODUCTION: Non-small cell lung cancer (NSCLC) is a worldwide malignance threatening human life. TGF-β/Smad signaling is known to regulate cell proliferation, differentiation, migration and growth. As the only co-Smad playing crucial roles in TGF-β signaling, Smad4 is reported to be frequently mut...

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Detalles Bibliográficos
Autores principales:	Wan, Rongxue, Xu, Xichao, Ma, Lunkun, Chen, Ying, Tang, Liling, Feng, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073448/ https://www.ncbi.nlm.nih.gov/pubmed/32210586 http://dx.doi.org/10.2147/OTT.S247015

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