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SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

The endolysosomal system fulfils a myriad of cellular functions predicated on regulated membrane identity progressions, collectively termed maturation. Mature or “late” endosomes are designated by small membrane‐bound GTPases Rab7 and Arl8b, which can either operate independently or collaborate to f...

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Detalles Bibliográficos
Autores principales: Jongsma, Marlieke LM, Bakker, Jeroen, Cabukusta, Birol, Liv, Nalan, van Elsland, Daphne, Fermie, Job, Akkermans, Jimmy LL, Kuijl, Coenraad, van der Zanden, Sabina Y, Janssen, Lennert, Hoogzaad, Denise, van der Kant, Rik, Wijdeven, Ruud H, Klumperman, Judith, Berlin, Ilana, Neefjes, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073467/
https://www.ncbi.nlm.nih.gov/pubmed/32080880
http://dx.doi.org/10.15252/embj.2019102301