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Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species

OBJECTIVE: The mechanism of enhanced radiosensitivity induced by mitochondrial uncoupling protein UCP2 was investigated in HeLa cells to provide a theoretical basis as a novel target for cervical cancer treatment. METHODS: HeLa cells were irradiated with 4 Gy X-radiation at 1.0 Gy/min. The expressio...

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Detalles Bibliográficos
Autores principales:	Liu, Cui Hua, Huang, Zhe Hao, Dong, Xin Yu, Zhang, Xin Qiang, Li, Yuan Hang, Zhao, Gang, Sun, Bao Sheng, Shen, Yan Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073473/ https://www.ncbi.nlm.nih.gov/pubmed/32190174 http://dx.doi.org/10.1155/2020/5135893

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