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Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impac...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073521/ https://www.ncbi.nlm.nih.gov/pubmed/32079075 http://dx.doi.org/10.3390/jcm9020535 |
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author | Nouri, Aria Cheng, Joseph S. Davies, Benjamin Kotter, Mark Schaller, Karl Tessitore, Enrico |
author_facet | Nouri, Aria Cheng, Joseph S. Davies, Benjamin Kotter, Mark Schaller, Karl Tessitore, Enrico |
author_sort | Nouri, Aria |
collection | PubMed |
description | Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impacts on the quality of life of those affected, as well as on their caregivers. DCM is triggered by a variety of degenerative changes in the neck, which affect one or more anatomical structures, including intervertebral discs, vertebrae, and spinal canal ligaments. These changes can also lead to structural abnormalities, leading to alterations in alignment, mobility, and stability. The principle unifying problem in this disease, regardless of the types of changes present, is injury to the spinal cord due to compression by static and/or dynamic forces. This review is partitioned into three segments that focus on key elements of the past, the present, and the future in the field, which serve to introduce the focus issue on “Degenerative Cervical Myelopathy and the Aging Spine”. Emerging from this review is that tremendous progress has been made in the field, particularly in recent years, and that there are exciting possibilities for further advancements of patient care. |
format | Online Article Text |
id | pubmed-7073521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70735212020-03-20 Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions Nouri, Aria Cheng, Joseph S. Davies, Benjamin Kotter, Mark Schaller, Karl Tessitore, Enrico J Clin Med Review Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impacts on the quality of life of those affected, as well as on their caregivers. DCM is triggered by a variety of degenerative changes in the neck, which affect one or more anatomical structures, including intervertebral discs, vertebrae, and spinal canal ligaments. These changes can also lead to structural abnormalities, leading to alterations in alignment, mobility, and stability. The principle unifying problem in this disease, regardless of the types of changes present, is injury to the spinal cord due to compression by static and/or dynamic forces. This review is partitioned into three segments that focus on key elements of the past, the present, and the future in the field, which serve to introduce the focus issue on “Degenerative Cervical Myelopathy and the Aging Spine”. Emerging from this review is that tremendous progress has been made in the field, particularly in recent years, and that there are exciting possibilities for further advancements of patient care. MDPI 2020-02-16 /pmc/articles/PMC7073521/ /pubmed/32079075 http://dx.doi.org/10.3390/jcm9020535 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Nouri, Aria Cheng, Joseph S. Davies, Benjamin Kotter, Mark Schaller, Karl Tessitore, Enrico Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title | Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title_full | Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title_fullStr | Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title_full_unstemmed | Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title_short | Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions |
title_sort | degenerative cervical myelopathy: a brief review of past perspectives, present developments, and future directions |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073521/ https://www.ncbi.nlm.nih.gov/pubmed/32079075 http://dx.doi.org/10.3390/jcm9020535 |
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