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Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions

Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impac...

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Autores principales: Nouri, Aria, Cheng, Joseph S., Davies, Benjamin, Kotter, Mark, Schaller, Karl, Tessitore, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073521/
https://www.ncbi.nlm.nih.gov/pubmed/32079075
http://dx.doi.org/10.3390/jcm9020535
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author Nouri, Aria
Cheng, Joseph S.
Davies, Benjamin
Kotter, Mark
Schaller, Karl
Tessitore, Enrico
author_facet Nouri, Aria
Cheng, Joseph S.
Davies, Benjamin
Kotter, Mark
Schaller, Karl
Tessitore, Enrico
author_sort Nouri, Aria
collection PubMed
description Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impacts on the quality of life of those affected, as well as on their caregivers. DCM is triggered by a variety of degenerative changes in the neck, which affect one or more anatomical structures, including intervertebral discs, vertebrae, and spinal canal ligaments. These changes can also lead to structural abnormalities, leading to alterations in alignment, mobility, and stability. The principle unifying problem in this disease, regardless of the types of changes present, is injury to the spinal cord due to compression by static and/or dynamic forces. This review is partitioned into three segments that focus on key elements of the past, the present, and the future in the field, which serve to introduce the focus issue on “Degenerative Cervical Myelopathy and the Aging Spine”. Emerging from this review is that tremendous progress has been made in the field, particularly in recent years, and that there are exciting possibilities for further advancements of patient care.
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spelling pubmed-70735212020-03-20 Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions Nouri, Aria Cheng, Joseph S. Davies, Benjamin Kotter, Mark Schaller, Karl Tessitore, Enrico J Clin Med Review Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a significant cause of disability in the elderly. It has important negative impacts on the quality of life of those affected, as well as on their caregivers. DCM is triggered by a variety of degenerative changes in the neck, which affect one or more anatomical structures, including intervertebral discs, vertebrae, and spinal canal ligaments. These changes can also lead to structural abnormalities, leading to alterations in alignment, mobility, and stability. The principle unifying problem in this disease, regardless of the types of changes present, is injury to the spinal cord due to compression by static and/or dynamic forces. This review is partitioned into three segments that focus on key elements of the past, the present, and the future in the field, which serve to introduce the focus issue on “Degenerative Cervical Myelopathy and the Aging Spine”. Emerging from this review is that tremendous progress has been made in the field, particularly in recent years, and that there are exciting possibilities for further advancements of patient care. MDPI 2020-02-16 /pmc/articles/PMC7073521/ /pubmed/32079075 http://dx.doi.org/10.3390/jcm9020535 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nouri, Aria
Cheng, Joseph S.
Davies, Benjamin
Kotter, Mark
Schaller, Karl
Tessitore, Enrico
Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title_full Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title_fullStr Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title_full_unstemmed Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title_short Degenerative Cervical Myelopathy: A Brief Review of Past Perspectives, Present Developments, and Future Directions
title_sort degenerative cervical myelopathy: a brief review of past perspectives, present developments, and future directions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073521/
https://www.ncbi.nlm.nih.gov/pubmed/32079075
http://dx.doi.org/10.3390/jcm9020535
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