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Development of Dual Functional Nucleic Acid Delivery Nanosystem for DNA Induced Silencing of Bcl-2 Oncogene

INTRODUCTION: Cancer treatment using functionalized vehicles in order to block involved genes has attracted a remarkable interest. In this study, we investigated the cellular uptake and cytotoxic effects of three sizes of anti Bcl-2 DNAi-conjugated gold nanoparticles by MCF-7 cells. METHODS: Three d...

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Detalles Bibliográficos
Autores principales: Karimi, Somayeh, Fouani, Mohamad Hassan, Moshaii, Ahmad, Nikkhah, Maryam, Hosseinkhani, Saman, Sheikhnejad, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073599/
https://www.ncbi.nlm.nih.gov/pubmed/32210560
http://dx.doi.org/10.2147/IJN.S236217