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Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice

Microglia, the resident macrophages, act as the first and main form of active immune defense in the central nervous system. Arginase 2 (Arg2) is an enzyme involved in L-arginine metabolism and is expressed in macrophages and nervous tissue. In this study, we determined whether the absence of Arg2 pl...

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Detalles Bibliográficos
Autores principales: Yin, Yuhua, Phạm, Thuỳ Linh, Shin, Juhee, Shin, Nara, Kang, Dong-Wook, Lee, Sun Yeul, Lee, Wonhyung, Kim, Cuk-Seong, Kim, Sang Ryong, Hong, Jinpyo, Kim, Dong-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073606/
https://www.ncbi.nlm.nih.gov/pubmed/31979015
http://dx.doi.org/10.3390/jcm9020305