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Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol
The present study aimed to assess the eighteen month follow-up patient-centered outcomes of a simple and predictable protocol for 3D-printed functional complete dentures manufactured using an improved poly(methyl methacrylate) (PMMA)–nanoTiO(2). A detailed morphological and structural characterizati...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073708/ https://www.ncbi.nlm.nih.gov/pubmed/31979345 http://dx.doi.org/10.3390/jcm9020324 |
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author | Cristache, Corina Marilena Totu, Eugenia Eftimie Iorgulescu, Gabriela Pantazi, Aida Dorobantu, Dorel Nechifor, Aurelia Cristina Isildak, Ibrahim Burlibasa, Mihai Nechifor, Gheorghe Enachescu, Marius |
author_facet | Cristache, Corina Marilena Totu, Eugenia Eftimie Iorgulescu, Gabriela Pantazi, Aida Dorobantu, Dorel Nechifor, Aurelia Cristina Isildak, Ibrahim Burlibasa, Mihai Nechifor, Gheorghe Enachescu, Marius |
author_sort | Cristache, Corina Marilena |
collection | PubMed |
description | The present study aimed to assess the eighteen month follow-up patient-centered outcomes of a simple and predictable protocol for 3D-printed functional complete dentures manufactured using an improved poly(methyl methacrylate) (PMMA)–nanoTiO(2). A detailed morphological and structural characterization of the PMMA–TiO(2) nanocomposite, using SEM, EDX, XRD, and AFM, after 3D-printing procedure and post-wearing micro-CT, was also performed. Methods: A total of 35 fully edentulous patients were enrolled in this prospective study. A 0.4% TiO(2)-nanoparticle-reinforced PMMA composite with improved mechanical strength, morphologically and structurally characterized, was used according to an additive computer-aided design and computer-aided manufacturing (CAD/CAM) protocol for complete denture fabrication. The protocol proposed involved a three-step appointment process. Before denture insertion, 1 week, 12 month, and 18-month follow up patients were evaluated via the Visual Analogue Scale (VAS, 0–10) and Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT), with a higher score meaning poor quality of life. Results: A total of 45 complete denture sets were inserted. OHIP-EDENT scored significantly better after 18 months of denture wearing, 20.43 (±4.42) compared to 52.57 (±8.16) before treatment; mean VAS was improved for all parameters assessed. Conclusions: Within the limitations of this study, we can state that the proposed workflow with the improved material used is a viable treatment option for patients diagnosed with complete edentulism. |
format | Online Article Text |
id | pubmed-7073708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70737082020-03-19 Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol Cristache, Corina Marilena Totu, Eugenia Eftimie Iorgulescu, Gabriela Pantazi, Aida Dorobantu, Dorel Nechifor, Aurelia Cristina Isildak, Ibrahim Burlibasa, Mihai Nechifor, Gheorghe Enachescu, Marius J Clin Med Article The present study aimed to assess the eighteen month follow-up patient-centered outcomes of a simple and predictable protocol for 3D-printed functional complete dentures manufactured using an improved poly(methyl methacrylate) (PMMA)–nanoTiO(2). A detailed morphological and structural characterization of the PMMA–TiO(2) nanocomposite, using SEM, EDX, XRD, and AFM, after 3D-printing procedure and post-wearing micro-CT, was also performed. Methods: A total of 35 fully edentulous patients were enrolled in this prospective study. A 0.4% TiO(2)-nanoparticle-reinforced PMMA composite with improved mechanical strength, morphologically and structurally characterized, was used according to an additive computer-aided design and computer-aided manufacturing (CAD/CAM) protocol for complete denture fabrication. The protocol proposed involved a three-step appointment process. Before denture insertion, 1 week, 12 month, and 18-month follow up patients were evaluated via the Visual Analogue Scale (VAS, 0–10) and Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT), with a higher score meaning poor quality of life. Results: A total of 45 complete denture sets were inserted. OHIP-EDENT scored significantly better after 18 months of denture wearing, 20.43 (±4.42) compared to 52.57 (±8.16) before treatment; mean VAS was improved for all parameters assessed. Conclusions: Within the limitations of this study, we can state that the proposed workflow with the improved material used is a viable treatment option for patients diagnosed with complete edentulism. MDPI 2020-01-23 /pmc/articles/PMC7073708/ /pubmed/31979345 http://dx.doi.org/10.3390/jcm9020324 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cristache, Corina Marilena Totu, Eugenia Eftimie Iorgulescu, Gabriela Pantazi, Aida Dorobantu, Dorel Nechifor, Aurelia Cristina Isildak, Ibrahim Burlibasa, Mihai Nechifor, Gheorghe Enachescu, Marius Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title | Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title_full | Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title_fullStr | Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title_full_unstemmed | Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title_short | Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol |
title_sort | eighteen months follow-up with patient-centered outcomes assessment of complete dentures manufactured using a hybrid nanocomposite and additive cad/cam protocol |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073708/ https://www.ncbi.nlm.nih.gov/pubmed/31979345 http://dx.doi.org/10.3390/jcm9020324 |
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