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Radiographic assessment of sarcopenia in the trauma setting: a systematic review
BACKGROUND: Compared with similarly injured patients of a younger age, elderly patients have worse outcomes from acute injury. One factor adversely affecting outcomes is sarcopenia, which has been assessed in healthy elderly populations through established clinical and radiological criteria. However...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073778/ https://www.ncbi.nlm.nih.gov/pubmed/32201738 http://dx.doi.org/10.1136/tsaco-2019-000414 |
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author | Zumsteg, Daniel M Chu, Caleb Everett Midwinter, Mark John |
author_facet | Zumsteg, Daniel M Chu, Caleb Everett Midwinter, Mark John |
author_sort | Zumsteg, Daniel M |
collection | PubMed |
description | BACKGROUND: Compared with similarly injured patients of a younger age, elderly patients have worse outcomes from acute injury. One factor adversely affecting outcomes is sarcopenia, which has been assessed in healthy elderly populations through established clinical and radiological criteria. However, in the acute care setting, no such criteria have been established. Sarcopenia has been opportunistically assessed via radiographic means but there is as of yet no gold standard. The purpose of this review is to summarize the radiological methods used to diagnose sarcopenia in the acute care setting, and suggest ways in which these methods may lead to a consensus definition of sarcopenia and its relationship to patient outcomes. METHODS: A systematic survey of medical databases was conducted, with 902 unique publications identified. After screening and application of inclusion and exclusion criteria, data regarding study population, outcome, imaging modality, and criteria for assessment of sarcopenia were extracted from 20 studies. Quality was assessed with the Newcastle-Ottawa Scale. RESULTS: CT was the imaging modality for 18 of the studies, with total psoas muscle cross-sectional area at the level of L3 and L4 being the dominant method for assessing sarcopenia. Adjustment for body morphology most commonly used patient height or L4 vertebral body area. The majority of articles found radiographically assessed sarcopenia to be significantly correlated to outcomes such as mortality, length of hospital stay, morbidity, and in-hospital complications CONCLUSIONS: Establishing a consistent definition would strengthen its applicability and generalizability to admission and discharge planning. LEVEL OF EVIDENCE: Systematic review, level III. |
format | Online Article Text |
id | pubmed-7073778 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-70737782020-03-20 Radiographic assessment of sarcopenia in the trauma setting: a systematic review Zumsteg, Daniel M Chu, Caleb Everett Midwinter, Mark John Trauma Surg Acute Care Open Systematic Review BACKGROUND: Compared with similarly injured patients of a younger age, elderly patients have worse outcomes from acute injury. One factor adversely affecting outcomes is sarcopenia, which has been assessed in healthy elderly populations through established clinical and radiological criteria. However, in the acute care setting, no such criteria have been established. Sarcopenia has been opportunistically assessed via radiographic means but there is as of yet no gold standard. The purpose of this review is to summarize the radiological methods used to diagnose sarcopenia in the acute care setting, and suggest ways in which these methods may lead to a consensus definition of sarcopenia and its relationship to patient outcomes. METHODS: A systematic survey of medical databases was conducted, with 902 unique publications identified. After screening and application of inclusion and exclusion criteria, data regarding study population, outcome, imaging modality, and criteria for assessment of sarcopenia were extracted from 20 studies. Quality was assessed with the Newcastle-Ottawa Scale. RESULTS: CT was the imaging modality for 18 of the studies, with total psoas muscle cross-sectional area at the level of L3 and L4 being the dominant method for assessing sarcopenia. Adjustment for body morphology most commonly used patient height or L4 vertebral body area. The majority of articles found radiographically assessed sarcopenia to be significantly correlated to outcomes such as mortality, length of hospital stay, morbidity, and in-hospital complications CONCLUSIONS: Establishing a consistent definition would strengthen its applicability and generalizability to admission and discharge planning. LEVEL OF EVIDENCE: Systematic review, level III. BMJ Publishing Group 2020-03-15 /pmc/articles/PMC7073778/ /pubmed/32201738 http://dx.doi.org/10.1136/tsaco-2019-000414 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Systematic Review Zumsteg, Daniel M Chu, Caleb Everett Midwinter, Mark John Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title | Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title_full | Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title_fullStr | Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title_full_unstemmed | Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title_short | Radiographic assessment of sarcopenia in the trauma setting: a systematic review |
title_sort | radiographic assessment of sarcopenia in the trauma setting: a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073778/ https://www.ncbi.nlm.nih.gov/pubmed/32201738 http://dx.doi.org/10.1136/tsaco-2019-000414 |
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