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Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes

Our aim was to illustrate our technique of sex-sparing (SS)-robot-assisted radical cystectomy (RARC) in female patients receiving an intracorporeal neobladder (iN). From January 2013 to June 2018, 11 female patients underwent SS-RARC-iN at a single tertiary referral center. Inclusion criteria were a...

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Autores principales: Tuderti, Gabriele, Mastroianni, Riccardo, Flammia, Simone, Ferriero, Mariaconsiglia, Leonardo, Costantino, Anceschi, Umberto, Brassetti, Aldo, Guaglianone, Salvatore, Gallucci, Michele, Simone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073846/
https://www.ncbi.nlm.nih.gov/pubmed/32093240
http://dx.doi.org/10.3390/jcm9020577
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author Tuderti, Gabriele
Mastroianni, Riccardo
Flammia, Simone
Ferriero, Mariaconsiglia
Leonardo, Costantino
Anceschi, Umberto
Brassetti, Aldo
Guaglianone, Salvatore
Gallucci, Michele
Simone, Giuseppe
author_facet Tuderti, Gabriele
Mastroianni, Riccardo
Flammia, Simone
Ferriero, Mariaconsiglia
Leonardo, Costantino
Anceschi, Umberto
Brassetti, Aldo
Guaglianone, Salvatore
Gallucci, Michele
Simone, Giuseppe
author_sort Tuderti, Gabriele
collection PubMed
description Our aim was to illustrate our technique of sex-sparing (SS)-robot-assisted radical cystectomy (RARC) in female patients receiving an intracorporeal neobladder (iN). From January 2013 to June 2018, 11 female patients underwent SS-RARC-iN at a single tertiary referral center. Inclusion criteria were a cT ≤ 2 N0 M0 bladder tumor at baseline imaging (CT or MRI) and an absence of tumors in the bladder neck, trigone and urethra at TURB. Baseline, perioperative, and outcomes at one year were reported. The median operative time was 255 min and the median hospital stay was seven days. Low-grade Clavien complications occurred in four patients (36.3%), while high-grade complications were not observed in any. Seven patients (63.7%) had an organ-confined disease at the pathologic specimen; nodal involvement and positive surgical margins were not detected in any of the cases. At a median follow-up of 28 months (IQR 14–51), no patients developed new onset of chronic kidney disease stage 3b. After one year, daytime and nighttime continence rates were 90.9% and 86.4% respectively. Quality of life as well as physical and emotional functioning improved significantly over time (all p ≤ 0.04), while urinary symptoms and sexual function worsened at three months with a significant recovery taking place at one year (all p ≤ 0.04). Overall, 8 out of 11 patients (72.7%) were sexually active at the 12-month evaluation. In select female patients, SS-RARC-iN is an oncologically sound procedure associated with favorable perioperative and functional outcomes.
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spelling pubmed-70738462020-03-19 Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes Tuderti, Gabriele Mastroianni, Riccardo Flammia, Simone Ferriero, Mariaconsiglia Leonardo, Costantino Anceschi, Umberto Brassetti, Aldo Guaglianone, Salvatore Gallucci, Michele Simone, Giuseppe J Clin Med Article Our aim was to illustrate our technique of sex-sparing (SS)-robot-assisted radical cystectomy (RARC) in female patients receiving an intracorporeal neobladder (iN). From January 2013 to June 2018, 11 female patients underwent SS-RARC-iN at a single tertiary referral center. Inclusion criteria were a cT ≤ 2 N0 M0 bladder tumor at baseline imaging (CT or MRI) and an absence of tumors in the bladder neck, trigone and urethra at TURB. Baseline, perioperative, and outcomes at one year were reported. The median operative time was 255 min and the median hospital stay was seven days. Low-grade Clavien complications occurred in four patients (36.3%), while high-grade complications were not observed in any. Seven patients (63.7%) had an organ-confined disease at the pathologic specimen; nodal involvement and positive surgical margins were not detected in any of the cases. At a median follow-up of 28 months (IQR 14–51), no patients developed new onset of chronic kidney disease stage 3b. After one year, daytime and nighttime continence rates were 90.9% and 86.4% respectively. Quality of life as well as physical and emotional functioning improved significantly over time (all p ≤ 0.04), while urinary symptoms and sexual function worsened at three months with a significant recovery taking place at one year (all p ≤ 0.04). Overall, 8 out of 11 patients (72.7%) were sexually active at the 12-month evaluation. In select female patients, SS-RARC-iN is an oncologically sound procedure associated with favorable perioperative and functional outcomes. MDPI 2020-02-20 /pmc/articles/PMC7073846/ /pubmed/32093240 http://dx.doi.org/10.3390/jcm9020577 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tuderti, Gabriele
Mastroianni, Riccardo
Flammia, Simone
Ferriero, Mariaconsiglia
Leonardo, Costantino
Anceschi, Umberto
Brassetti, Aldo
Guaglianone, Salvatore
Gallucci, Michele
Simone, Giuseppe
Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title_full Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title_fullStr Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title_full_unstemmed Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title_short Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes
title_sort sex-sparing robot-assisted radical cystectomy with intracorporeal padua ileal neobladder in female: surgical technique, perioperative, oncologic and functional outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073846/
https://www.ncbi.nlm.nih.gov/pubmed/32093240
http://dx.doi.org/10.3390/jcm9020577
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