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Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population

Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare but severe complication of bisphosphonate therapy. To understand this condition better, data collection is essential. Although the number of scientific papers about this subject is large, to date only a few multic...

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Autores principales: Vereb, Tamás, Boda, Krisztina, Czakó, László, Vaszilkó, Mihály, Fülöp, Gábor, Klenk, Gusztáv, Janovszky, Ágnes, Oberna, Ferenc, Piffkó, József, Seres, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073980/
https://www.ncbi.nlm.nih.gov/pubmed/32033299
http://dx.doi.org/10.3390/jcm9020426
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author Vereb, Tamás
Boda, Krisztina
Czakó, László
Vaszilkó, Mihály
Fülöp, Gábor
Klenk, Gusztáv
Janovszky, Ágnes
Oberna, Ferenc
Piffkó, József
Seres, László
author_facet Vereb, Tamás
Boda, Krisztina
Czakó, László
Vaszilkó, Mihály
Fülöp, Gábor
Klenk, Gusztáv
Janovszky, Ágnes
Oberna, Ferenc
Piffkó, József
Seres, László
author_sort Vereb, Tamás
collection PubMed
description Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare but severe complication of bisphosphonate therapy. To understand this condition better, data collection is essential. Although the number of scientific papers about this subject is large, to date only a few multicenter reports have been published. Study design: We present a novel cloud-based data collection system for the evaluation of the risk factors of bisphosphonate-related osteonecrosis of the jaws. Web-based questionnaire and database have been set up and made available to voluntary researchers and clinicians in oral and maxillofacial surgery in Hungary and Slovakia. Results: To date, fifteen colleagues from eight maxillofacial units have joined the study. Data of 180 patients have been recorded. Collected data were statistically analysed and evaluated from an epidemiological point of view. Conclusions: Authors consider cloud-based multicenter data collection a useful tool that allows for real-time collaboration between users, facilitates fast data entry and analysis, and thus considerably contributes to widening our knowledge of bisphosphonate-related osteonecrosis of the jaws.
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spelling pubmed-70739802020-03-19 Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population Vereb, Tamás Boda, Krisztina Czakó, László Vaszilkó, Mihály Fülöp, Gábor Klenk, Gusztáv Janovszky, Ágnes Oberna, Ferenc Piffkó, József Seres, László J Clin Med Article Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare but severe complication of bisphosphonate therapy. To understand this condition better, data collection is essential. Although the number of scientific papers about this subject is large, to date only a few multicenter reports have been published. Study design: We present a novel cloud-based data collection system for the evaluation of the risk factors of bisphosphonate-related osteonecrosis of the jaws. Web-based questionnaire and database have been set up and made available to voluntary researchers and clinicians in oral and maxillofacial surgery in Hungary and Slovakia. Results: To date, fifteen colleagues from eight maxillofacial units have joined the study. Data of 180 patients have been recorded. Collected data were statistically analysed and evaluated from an epidemiological point of view. Conclusions: Authors consider cloud-based multicenter data collection a useful tool that allows for real-time collaboration between users, facilitates fast data entry and analysis, and thus considerably contributes to widening our knowledge of bisphosphonate-related osteonecrosis of the jaws. MDPI 2020-02-05 /pmc/articles/PMC7073980/ /pubmed/32033299 http://dx.doi.org/10.3390/jcm9020426 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vereb, Tamás
Boda, Krisztina
Czakó, László
Vaszilkó, Mihály
Fülöp, Gábor
Klenk, Gusztáv
Janovszky, Ágnes
Oberna, Ferenc
Piffkó, József
Seres, László
Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title_full Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title_fullStr Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title_full_unstemmed Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title_short Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population
title_sort cloud-based multicenter data collection and epidemiologic analysis of bisphosphonate-related osteonecrosis of the jaws in a central european population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073980/
https://www.ncbi.nlm.nih.gov/pubmed/32033299
http://dx.doi.org/10.3390/jcm9020426
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