Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment

Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway obstruction during sleep resulting in intermittent hypoxemia and sleep fragmentation. Research has recently increasingly focused on the impact of OSA on the brain’s structure and function, in particular as...

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Detalles Bibliográficos
Autores principales: Lajoie, Annie C., Lafontaine, Anne-Louise, Kimoff, R. John, Kaminska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073991/
https://www.ncbi.nlm.nih.gov/pubmed/31973065
http://dx.doi.org/10.3390/jcm9020297
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author Lajoie, Annie C.
Lafontaine, Anne-Louise
Kimoff, R. John
Kaminska, Marta
author_facet Lajoie, Annie C.
Lafontaine, Anne-Louise
Kimoff, R. John
Kaminska, Marta
author_sort Lajoie, Annie C.
collection PubMed
description Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway obstruction during sleep resulting in intermittent hypoxemia and sleep fragmentation. Research has recently increasingly focused on the impact of OSA on the brain’s structure and function, in particular as this relates to neurodegenerative diseases. This article reviews the links between OSA and neurodegenerative disease, focusing on Parkinson’s disease, including proposed pathogenic mechanisms and current knowledge on the effects of treatment.
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spelling pubmed-70739912020-03-19 Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment Lajoie, Annie C. Lafontaine, Anne-Louise Kimoff, R. John Kaminska, Marta J Clin Med Review Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway obstruction during sleep resulting in intermittent hypoxemia and sleep fragmentation. Research has recently increasingly focused on the impact of OSA on the brain’s structure and function, in particular as this relates to neurodegenerative diseases. This article reviews the links between OSA and neurodegenerative disease, focusing on Parkinson’s disease, including proposed pathogenic mechanisms and current knowledge on the effects of treatment. MDPI 2020-01-21 /pmc/articles/PMC7073991/ /pubmed/31973065 http://dx.doi.org/10.3390/jcm9020297 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lajoie, Annie C.
Lafontaine, Anne-Louise
Kimoff, R. John
Kaminska, Marta
Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title_full Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title_fullStr Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title_full_unstemmed Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title_short Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment
title_sort obstructive sleep apnea in neurodegenerative disorders: current evidence in support of benefit from sleep apnea treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073991/
https://www.ncbi.nlm.nih.gov/pubmed/31973065
http://dx.doi.org/10.3390/jcm9020297
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