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Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension
Vascular remodeling is considered a key event in the pathogenesis of pulmonary arterial hypertension (PAH). However, mechanisms of gaining the proliferative phenotype by pulmonary vascular cells are still unresolved. Due to well-established pyruvate dehydrogenase (PDH) deficiency in PAH pathogenesis...
Autores principales: | Valuparampil Varghese, Mathews, James, Joel, Eccles, Cody A, Niihori, Maki, Rafikova, Olga, Rafikov, Ruslan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074087/ https://www.ncbi.nlm.nih.gov/pubmed/32041182 http://dx.doi.org/10.3390/jcm9020443 |
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