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Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma
Due to the growing availability of imaging examinations the percentage of patients with incidentally diagnosed adrenal tumors has increased. The vast majority of these lesions are benign, non-functioning adenomas, although according to various estimates even up to 30%–50% of patients with adrenal in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074127/ https://www.ncbi.nlm.nih.gov/pubmed/32050625 http://dx.doi.org/10.3390/medicina56020069 |
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author | Szychlińska, Magdalena Baranowska-Jurkun, Angelika Matuszewski, Wojciech Wołos-Kłosowicz, Katarzyna Bandurska-Stankiewicz, Elżbieta |
author_facet | Szychlińska, Magdalena Baranowska-Jurkun, Angelika Matuszewski, Wojciech Wołos-Kłosowicz, Katarzyna Bandurska-Stankiewicz, Elżbieta |
author_sort | Szychlińska, Magdalena |
collection | PubMed |
description | Due to the growing availability of imaging examinations the percentage of patients with incidentally diagnosed adrenal tumors has increased. The vast majority of these lesions are benign, non-functioning adenomas, although according to various estimates even up to 30%–50% of patients with adrenal incidentaloma may present biochemical hypercortisolemia, without typical clinical features of Cushing’s syndrome. Adrenal adenomas secreting small amounts of glucocorticoids may cause morphological and functional changes in the myocardium and blood vessels. Early stages of cardiovascular remodeling may be observed among asymptomatic patients with adrenal adenoma. Vascular changes precede the development of cardiovascular diseases and can increase morbidity and mortality in patients with adrenal incidentaloma. This risk may result not only from the traditional risk factors. Seemingly hormonally inactive adrenal tumors can indeed produce small amounts of glucocorticoids that have metabolic implications. Therefore, evaluation of patients with incidental adrenal findings presenting with subclinical cardiovascular disease seems of particular importance. |
format | Online Article Text |
id | pubmed-7074127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70741272020-03-19 Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma Szychlińska, Magdalena Baranowska-Jurkun, Angelika Matuszewski, Wojciech Wołos-Kłosowicz, Katarzyna Bandurska-Stankiewicz, Elżbieta Medicina (Kaunas) Review Due to the growing availability of imaging examinations the percentage of patients with incidentally diagnosed adrenal tumors has increased. The vast majority of these lesions are benign, non-functioning adenomas, although according to various estimates even up to 30%–50% of patients with adrenal incidentaloma may present biochemical hypercortisolemia, without typical clinical features of Cushing’s syndrome. Adrenal adenomas secreting small amounts of glucocorticoids may cause morphological and functional changes in the myocardium and blood vessels. Early stages of cardiovascular remodeling may be observed among asymptomatic patients with adrenal adenoma. Vascular changes precede the development of cardiovascular diseases and can increase morbidity and mortality in patients with adrenal incidentaloma. This risk may result not only from the traditional risk factors. Seemingly hormonally inactive adrenal tumors can indeed produce small amounts of glucocorticoids that have metabolic implications. Therefore, evaluation of patients with incidental adrenal findings presenting with subclinical cardiovascular disease seems of particular importance. MDPI 2020-02-10 /pmc/articles/PMC7074127/ /pubmed/32050625 http://dx.doi.org/10.3390/medicina56020069 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Szychlińska, Magdalena Baranowska-Jurkun, Angelika Matuszewski, Wojciech Wołos-Kłosowicz, Katarzyna Bandurska-Stankiewicz, Elżbieta Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title | Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title_full | Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title_fullStr | Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title_full_unstemmed | Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title_short | Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma |
title_sort | markers of subclinical cardiovascular disease in patients with adrenal incidentaloma |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074127/ https://www.ncbi.nlm.nih.gov/pubmed/32050625 http://dx.doi.org/10.3390/medicina56020069 |
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