IGFBP-1 in Cardiometabolic Pathophysiology—Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice

We have previously reported that overexpression of human insulin-like growth factor binding protein (IGFBP)-1 in mice leads to vascular insulin sensitization, increased nitric oxide bioavailability, reduced atherosclerosis, and enhanced vascular repair, and in the setting of obesity improves glucose...

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Detalles Bibliográficos
Autores principales: Haywood, Natalie J, Slater, Thomas A, Drozd, Michael, Warmke, Nele, Matthews, Connor, Cordell, Paul A, Smith, Jessica, Rainford, Jethro, Cheema, Harneet, Maher, Caitlyn, Bridge, Katherine I, Yuldasheva, Nadira Y, Cubbon, Richard M, Kearney, Mark T, Wheatcroft, Stephen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074193/
https://www.ncbi.nlm.nih.gov/pubmed/32190801
http://dx.doi.org/10.1210/jendso/bvz006

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