Cargando…

Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with an increased risk of heart failure, stroke, dementia, and death. Recently, titin-truncating variants (TTNtv), which are predominantly associated with dilated cardiomyopathy (DCM), were associated with early-ons...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vad, Oliver Bundgaard, Paludan-Müller, Christian, Ahlberg, Gustav, Kalstø, Silje Madeleine, Ghouse, Jonas, Andreasen, Laura, Haunsø, Stig, Tveit, Arnljot, Sajadieh, Ahmad, Christophersen, Ingrid Elisabeth, Svendsen, Jesper Hastrup, Olesen, Morten Salling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074234/ https://www.ncbi.nlm.nih.gov/pubmed/32013268 http://dx.doi.org/10.3390/jcm9020372

Ejemplares similares

Genome-wide association study identifies 18 novel loci associated with left atrial volume and function
por: Ahlberg, Gustav, et al.
Publicado: (2021)

Analyses of more than 60,000 exomes questions the role of numerous genes previously associated with dilated cardiomyopathy
por: Nouhravesh, Nina, et al.
Publicado: (2016)

Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation
por: Vad, Oliver Bundgaard, et al.
Publicado: (2022)

Screening of the I(to) Regulatory Subunit Klf15 in Patients with Early-Onset Lone Atrial Fibrillation
por: Nielsen, Morten Wagner, et al.
Publicado: (2013)

Mutation analysis of the candidate genes SCN1B-4B, FHL1, and LMNA in patients with arrhythmogenic right ventricular cardiomyopathy
por: Refsgaard, Lena, et al.
Publicado: (2012)

A Novel Loss-of-Function Variant in the Chloride Ion Channel Gene Clcn2 Associates with Atrial Fibrillation
por: Hansen, Thea Hyttel, et al.
Publicado: (2020)

Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis
por: Andreasen, Laura, et al.
Publicado: (2020)

Cardiac magnetic resonance systematically overestimates mitral regurgitations by the indirect method
por: Bertelsen, Litten, et al.
Publicado: (2020)

Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest
por: Andreasen, Laura, et al.
Publicado: (2018)

New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants
por: Andreasen, Charlotte, et al.
Publicado: (2013)

CineECG analysis provides new insights into Familial ST-segment Depression Syndrome
por: Frosted, Rasmus, et al.
Publicado: (2023)

Association of Common and Rare Genetic Variation in the 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
por: Ghouse, Jonas, et al.
Publicado: (2022)

Verification of threshold for image intensity ratio analyses of late gadolinium enhancement magnetic resonance imaging of left atrial fibrosis in 1.5T scans
por: Bertelsen, Litten, et al.
Publicado: (2019)

Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
por: Ahlberg, Gustav, et al.
Publicado: (2018)

Electrocardiographic Precordial ST‐Segment Deviations and the Risk of Cardiovascular Death: Results From the Copenhagen ECG Study
por: Rasmussen, Peter Vibe, et al.
Publicado: (2014)

New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome
por: Yang, Ren-Qiang, et al.
Publicado: (2014)

Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse
por: Hadji-Turdeghal, Katra, et al.
Publicado: (2020)

Atrial Fibrillation Genetics Update: Toward Clinical Implementation
por: Kalstø, Silje Madeleine, et al.
Publicado: (2019)

Prevalence and incidence rates of atrial fibrillation in Norway 2004–2014
por: Kjerpeseth, Lars Jøran, et al.
Publicado: (2021)

Loss-of-Function Variants in the SYNPO2L Gene Are Associated With Atrial Fibrillation
por: Clausen, Alexander Guldmann, et al.
Publicado: (2021)

A polymorphism associated with increased levels of YKL-40 and the risk of early onset of lone atrial fibrillation
por: Henningsen, Kristoffer M A, et al.
Publicado: (2013)

Quantitative Proteomics of Human Heart Samples Collected In Vivo Reveal the Remodeled Protein Landscape of Dilated Left Atrium Without Atrial Fibrillation
por: Linscheid, Nora, et al.
Publicado: (2020)

Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis
por: Winkel, Bo G, et al.
Publicado: (2011)

Systolic Blood Pressure and Effects of Screening for Atrial Fibrillation With Long-Term Continuous Monitoring (a LOOP Substudy)
por: Xing, Lucas Yixi, et al.
Publicado: (2022)

Severity and Etiology of Incident Stroke in Patients Screened for Atrial Fibrillation vs Usual Care and the Impact of Prior Stroke: A Post Hoc Analysis of the LOOP Randomized Clinical Trial
por: Diederichsen, Søren Zöga, et al.
Publicado: (2022)

Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation
por: Olesen, Morten S, et al.
Publicado: (2012)

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease
por: Holst, Anders G., et al.
Publicado: (2009)

High prevalence of genetic variants previously associated with LQT syndrome in new exome data
por: Refsgaard, Lena, et al.
Publicado: (2012)

Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population
por: Nielsen, Jonas B., et al.
Publicado: (2014)

Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block
por: Skov, Morten W., et al.
Publicado: (2018)

Explaining deep neural networks for knowledge discovery in electrocardiogram analysis
por: Hicks, Steven A., et al.
Publicado: (2021)

DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine
por: Thambawita, Vajira, et al.
Publicado: (2021)

Feasibility of Patient-Managed ECG Recordings to Detect the Time of Atrial Fibrillation Recurrence after Electrical Cardioversion: Results from the PRE-ELECTRIC Study
por: Andersen, Elizabeth Lyster, et al.
Publicado: (2023)

Risk of atrial fibrillation and stroke in rheumatoid arthritis: Danish nationwide cohort study
por: Lindhardsen, Jesper, et al.
Publicado: (2012)

Business as (un)usual: A qualitative study of clerkship experiences during a health crisis
por: Noerholk, Laerke Marijke, et al.
Publicado: (2022)

Prevalence of abnormal glucose metabolism in atrial fibrillation: A case control study in 75-year old subjects
por: Johansen, Odd Erik, et al.
Publicado: (2008)

Incidence and Risk Factors of Ventricular Fibrillation Before Primary Angioplasty in Patients With First ST‐Elevation Myocardial Infarction: A Nationwide Study in Denmark
por: Jabbari, Reza, et al.
Publicado: (2015)

Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study
por: Xing, Lucas Yixi, et al.
Publicado: (2023)

Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study
por: Xing, Lucas Yixi, et al.
Publicado: (2023)

Individual variation and intraclass correlation in arachidonic acid and eicosapentaenoic acid in chicken muscle
por: Haug, Anna, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tq246t7aijbl6akugg8d04b9p7