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Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole

Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted fl...

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Autores principales: Sborgia, Giancarlo, Niro, Alfredo, Tritto, Tiziana, Albano, Valeria, Sborgia, Luigi, Sborgia, Alessandra, Donghia, Rossella, Giancipoli, Ermete, Coassin, Marco, Pastore, Valentina, Giuliani, Gianluigi, Lorenzi, Umberto, Romano, Mario R., Boscia, Francesco, Alessio, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074367/
https://www.ncbi.nlm.nih.gov/pubmed/32085592
http://dx.doi.org/10.3390/jcm9020556
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author Sborgia, Giancarlo
Niro, Alfredo
Tritto, Tiziana
Albano, Valeria
Sborgia, Luigi
Sborgia, Alessandra
Donghia, Rossella
Giancipoli, Ermete
Coassin, Marco
Pastore, Valentina
Giuliani, Gianluigi
Lorenzi, Umberto
Romano, Mario R.
Boscia, Francesco
Alessio, Giovanni
author_facet Sborgia, Giancarlo
Niro, Alfredo
Tritto, Tiziana
Albano, Valeria
Sborgia, Luigi
Sborgia, Alessandra
Donghia, Rossella
Giancipoli, Ermete
Coassin, Marco
Pastore, Valentina
Giuliani, Gianluigi
Lorenzi, Umberto
Romano, Mario R.
Boscia, Francesco
Alessio, Giovanni
author_sort Sborgia, Giancarlo
collection PubMed
description Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted flap technique for LMH. Methods: In this prospective comparative study, 26 patients after LMH surgical closure were enrolled. The whole sample was equally divided into two groups. In Group 1 (trained), patients underwent a double cycle of microperimetric biofeedback, using structured light stimulus plus acoustic tone; in Group 2 (control), patients underwent scheduled visits. We analyzed visual acuity, retinal sensitivity at central 12° (macular sensitivity, MS) and 4° (central macular sensitivity, CMS), and fixation stability over twelve months. Results: Visual acuity improved mainly in the trained group, without any significant differences between the groups (p > 0.05). Only after training did MS significantly improve (p = 0.01). CMS more significantly improved in the trained (p < 0.001) than the control group (p < 0.01) (Group 1 vs. 2, p = 0.004). Only in the trained group did fixation significantly improve (3 months, p ≤ 0.03; 12 months, p ≤ 0.01). An equality test on matched data confirmed a greater significant improvement of CMS (p ≤ 0.02) at all follow-up and fixation (p ≤ 0.02) at last follow-up after training. Conclusions: Microperimetric biofeedback consolidates and increases the improvement of retinal sensitivity and fixation gained after successful inverted flap technique.
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spelling pubmed-70743672020-03-20 Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole Sborgia, Giancarlo Niro, Alfredo Tritto, Tiziana Albano, Valeria Sborgia, Luigi Sborgia, Alessandra Donghia, Rossella Giancipoli, Ermete Coassin, Marco Pastore, Valentina Giuliani, Gianluigi Lorenzi, Umberto Romano, Mario R. Boscia, Francesco Alessio, Giovanni J Clin Med Article Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted flap technique for LMH. Methods: In this prospective comparative study, 26 patients after LMH surgical closure were enrolled. The whole sample was equally divided into two groups. In Group 1 (trained), patients underwent a double cycle of microperimetric biofeedback, using structured light stimulus plus acoustic tone; in Group 2 (control), patients underwent scheduled visits. We analyzed visual acuity, retinal sensitivity at central 12° (macular sensitivity, MS) and 4° (central macular sensitivity, CMS), and fixation stability over twelve months. Results: Visual acuity improved mainly in the trained group, without any significant differences between the groups (p > 0.05). Only after training did MS significantly improve (p = 0.01). CMS more significantly improved in the trained (p < 0.001) than the control group (p < 0.01) (Group 1 vs. 2, p = 0.004). Only in the trained group did fixation significantly improve (3 months, p ≤ 0.03; 12 months, p ≤ 0.01). An equality test on matched data confirmed a greater significant improvement of CMS (p ≤ 0.02) at all follow-up and fixation (p ≤ 0.02) at last follow-up after training. Conclusions: Microperimetric biofeedback consolidates and increases the improvement of retinal sensitivity and fixation gained after successful inverted flap technique. MDPI 2020-02-18 /pmc/articles/PMC7074367/ /pubmed/32085592 http://dx.doi.org/10.3390/jcm9020556 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sborgia, Giancarlo
Niro, Alfredo
Tritto, Tiziana
Albano, Valeria
Sborgia, Luigi
Sborgia, Alessandra
Donghia, Rossella
Giancipoli, Ermete
Coassin, Marco
Pastore, Valentina
Giuliani, Gianluigi
Lorenzi, Umberto
Romano, Mario R.
Boscia, Francesco
Alessio, Giovanni
Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title_full Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title_fullStr Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title_full_unstemmed Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title_short Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
title_sort microperimetric biofeedback training after successful inverted flap technique for large macular hole
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074367/
https://www.ncbi.nlm.nih.gov/pubmed/32085592
http://dx.doi.org/10.3390/jcm9020556
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