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Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole
Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted fl...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074367/ https://www.ncbi.nlm.nih.gov/pubmed/32085592 http://dx.doi.org/10.3390/jcm9020556 |
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author | Sborgia, Giancarlo Niro, Alfredo Tritto, Tiziana Albano, Valeria Sborgia, Luigi Sborgia, Alessandra Donghia, Rossella Giancipoli, Ermete Coassin, Marco Pastore, Valentina Giuliani, Gianluigi Lorenzi, Umberto Romano, Mario R. Boscia, Francesco Alessio, Giovanni |
author_facet | Sborgia, Giancarlo Niro, Alfredo Tritto, Tiziana Albano, Valeria Sborgia, Luigi Sborgia, Alessandra Donghia, Rossella Giancipoli, Ermete Coassin, Marco Pastore, Valentina Giuliani, Gianluigi Lorenzi, Umberto Romano, Mario R. Boscia, Francesco Alessio, Giovanni |
author_sort | Sborgia, Giancarlo |
collection | PubMed |
description | Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted flap technique for LMH. Methods: In this prospective comparative study, 26 patients after LMH surgical closure were enrolled. The whole sample was equally divided into two groups. In Group 1 (trained), patients underwent a double cycle of microperimetric biofeedback, using structured light stimulus plus acoustic tone; in Group 2 (control), patients underwent scheduled visits. We analyzed visual acuity, retinal sensitivity at central 12° (macular sensitivity, MS) and 4° (central macular sensitivity, CMS), and fixation stability over twelve months. Results: Visual acuity improved mainly in the trained group, without any significant differences between the groups (p > 0.05). Only after training did MS significantly improve (p = 0.01). CMS more significantly improved in the trained (p < 0.001) than the control group (p < 0.01) (Group 1 vs. 2, p = 0.004). Only in the trained group did fixation significantly improve (3 months, p ≤ 0.03; 12 months, p ≤ 0.01). An equality test on matched data confirmed a greater significant improvement of CMS (p ≤ 0.02) at all follow-up and fixation (p ≤ 0.02) at last follow-up after training. Conclusions: Microperimetric biofeedback consolidates and increases the improvement of retinal sensitivity and fixation gained after successful inverted flap technique. |
format | Online Article Text |
id | pubmed-7074367 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70743672020-03-20 Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole Sborgia, Giancarlo Niro, Alfredo Tritto, Tiziana Albano, Valeria Sborgia, Luigi Sborgia, Alessandra Donghia, Rossella Giancipoli, Ermete Coassin, Marco Pastore, Valentina Giuliani, Gianluigi Lorenzi, Umberto Romano, Mario R. Boscia, Francesco Alessio, Giovanni J Clin Med Article Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected. Microperimetric biofeedback can improve visual function in macular pathologies. We evaluated the efficacy of biofeedback on macular function after successful inverted flap technique for LMH. Methods: In this prospective comparative study, 26 patients after LMH surgical closure were enrolled. The whole sample was equally divided into two groups. In Group 1 (trained), patients underwent a double cycle of microperimetric biofeedback, using structured light stimulus plus acoustic tone; in Group 2 (control), patients underwent scheduled visits. We analyzed visual acuity, retinal sensitivity at central 12° (macular sensitivity, MS) and 4° (central macular sensitivity, CMS), and fixation stability over twelve months. Results: Visual acuity improved mainly in the trained group, without any significant differences between the groups (p > 0.05). Only after training did MS significantly improve (p = 0.01). CMS more significantly improved in the trained (p < 0.001) than the control group (p < 0.01) (Group 1 vs. 2, p = 0.004). Only in the trained group did fixation significantly improve (3 months, p ≤ 0.03; 12 months, p ≤ 0.01). An equality test on matched data confirmed a greater significant improvement of CMS (p ≤ 0.02) at all follow-up and fixation (p ≤ 0.02) at last follow-up after training. Conclusions: Microperimetric biofeedback consolidates and increases the improvement of retinal sensitivity and fixation gained after successful inverted flap technique. MDPI 2020-02-18 /pmc/articles/PMC7074367/ /pubmed/32085592 http://dx.doi.org/10.3390/jcm9020556 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sborgia, Giancarlo Niro, Alfredo Tritto, Tiziana Albano, Valeria Sborgia, Luigi Sborgia, Alessandra Donghia, Rossella Giancipoli, Ermete Coassin, Marco Pastore, Valentina Giuliani, Gianluigi Lorenzi, Umberto Romano, Mario R. Boscia, Francesco Alessio, Giovanni Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title | Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title_full | Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title_fullStr | Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title_full_unstemmed | Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title_short | Microperimetric Biofeedback Training After Successful Inverted Flap Technique for Large Macular Hole |
title_sort | microperimetric biofeedback training after successful inverted flap technique for large macular hole |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074367/ https://www.ncbi.nlm.nih.gov/pubmed/32085592 http://dx.doi.org/10.3390/jcm9020556 |
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