Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced Form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone

The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal agent, we converted the quinone avarone into...

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Detalles Bibliográficos
Autores principales: Imperatore, Concetta, Gimmelli, Roberto, Persico, Marco, Casertano, Marcello, Guidi, Alessandra, Saccoccia, Fulvio, Ruberti, Giovina, Luciano, Paolo, Aiello, Anna, Parapini, Silvia, Avunduk, Sibel, Basilico, Nicoletta, Fattorusso, Caterina, Menna, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074381/
https://www.ncbi.nlm.nih.gov/pubmed/32075136
http://dx.doi.org/10.3390/md18020112

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