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Identification of ADPKD-Related Genes and Pathways in Cells Overexpressing PKD2

Consistent with the gene dosage effect hypothesis, renal cysts can arise in transgenic murine models overexpressing either PKD1 or PKD2, which are causal genes for autosomal dominant polycystic kidney disease (ADPKD). To determine whether PKD gene overexpression is a universal mechanism driving cyst...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhe, Dang, Yanna, Wang, Zizengceng, Wang, Huanan, Pan, Yuchun, He, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074416/ https://www.ncbi.nlm.nih.gov/pubmed/31979107 http://dx.doi.org/10.3390/genes11020122

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