Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension

Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 0...

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Detalles Bibliográficos
Autores principales: Richter, Manuel J., Harutyunova, Satenik, Bollmann, Tom, Classen, Simon, Fuge, Jan, Gall, Henning, Gerhardt, Felix, Ghofrani, Hossein A., Gunkel, Hartmut, Grünig, Ekkehard, Halank, Michael, Heine, Alexander, Klose, Hans, Lange, Tobias J., Neurohr, Claus, Nickolaus, Kai, Opitz, Christian F., Rosenkranz, Stephan, Seyfarth, Hans-Jürgen, Tello, Khodr, Ewert, Ralf, Olsson, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074510/
https://www.ncbi.nlm.nih.gov/pubmed/32206306
http://dx.doi.org/10.1177/2045894020910136
Descripción
Sumario:Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.

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