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Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training

Both pulmonary function and autonomic function are impaired in patients with Parkinson’s diseases (PD). This study tested the hypothesis that respiratory muscle training (RMT) can not only improve pulmonary function, but also simultaneously improve cardiovascular autonomic function and short-term fu...

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Autores principales: Huang, Chih-Cheng, Lai, Yun-Ru, Wu, Fu-An, Kuo, Nai-Ying, Tsai, Yuh-Chyn, Cheng, Ben-Chung, Tsai, Nai-Wen, Lu, Cheng-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074532/
https://www.ncbi.nlm.nih.gov/pubmed/31979103
http://dx.doi.org/10.3390/jcm9020316
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author Huang, Chih-Cheng
Lai, Yun-Ru
Wu, Fu-An
Kuo, Nai-Ying
Tsai, Yuh-Chyn
Cheng, Ben-Chung
Tsai, Nai-Wen
Lu, Cheng-Hsien
author_facet Huang, Chih-Cheng
Lai, Yun-Ru
Wu, Fu-An
Kuo, Nai-Ying
Tsai, Yuh-Chyn
Cheng, Ben-Chung
Tsai, Nai-Wen
Lu, Cheng-Hsien
author_sort Huang, Chih-Cheng
collection PubMed
description Both pulmonary function and autonomic function are impaired in patients with Parkinson’s diseases (PD). This study tested the hypothesis that respiratory muscle training (RMT) can not only improve pulmonary function, but also simultaneously improve cardiovascular autonomic function and short-term functional outcomes in patients with PD. Pulmonary function was measured by the forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum inspiratory pressures (MIP), and maximum expiratory pressures (MEP). Cardiovascular autonomic function was measured by the heart rate response to deep breathing (HRDB), Valsalva ratio, baroreflex sensitivity, and spectral analysis. The functional and severity scores were measured by the Hoehn and Yahr stage and Unified Parkinson’s Disease Rating Scale (UPDRS). These measures were evaluated in patients with PD before and after 3 months of RMT, compared with a control group of PD patients without RMT. The results showed significant improvement of clinical scores (total UPDRS and UPDRS I, II and III) after RMT (p < 0.0001). Concerning pulmonary function, the parameters of MIP and MEP improved significantly. The parameters of cardiovascular function also improved after RMT, although only HRDB reached statistical significance. Based on the results of our study, RMT can not only improve both pulmonary and cardiovascular autonomic function, but can also improve short-term functional outcomes in patients with PD.
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spelling pubmed-70745322020-03-20 Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training Huang, Chih-Cheng Lai, Yun-Ru Wu, Fu-An Kuo, Nai-Ying Tsai, Yuh-Chyn Cheng, Ben-Chung Tsai, Nai-Wen Lu, Cheng-Hsien J Clin Med Article Both pulmonary function and autonomic function are impaired in patients with Parkinson’s diseases (PD). This study tested the hypothesis that respiratory muscle training (RMT) can not only improve pulmonary function, but also simultaneously improve cardiovascular autonomic function and short-term functional outcomes in patients with PD. Pulmonary function was measured by the forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum inspiratory pressures (MIP), and maximum expiratory pressures (MEP). Cardiovascular autonomic function was measured by the heart rate response to deep breathing (HRDB), Valsalva ratio, baroreflex sensitivity, and spectral analysis. The functional and severity scores were measured by the Hoehn and Yahr stage and Unified Parkinson’s Disease Rating Scale (UPDRS). These measures were evaluated in patients with PD before and after 3 months of RMT, compared with a control group of PD patients without RMT. The results showed significant improvement of clinical scores (total UPDRS and UPDRS I, II and III) after RMT (p < 0.0001). Concerning pulmonary function, the parameters of MIP and MEP improved significantly. The parameters of cardiovascular function also improved after RMT, although only HRDB reached statistical significance. Based on the results of our study, RMT can not only improve both pulmonary and cardiovascular autonomic function, but can also improve short-term functional outcomes in patients with PD. MDPI 2020-01-22 /pmc/articles/PMC7074532/ /pubmed/31979103 http://dx.doi.org/10.3390/jcm9020316 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Huang, Chih-Cheng
Lai, Yun-Ru
Wu, Fu-An
Kuo, Nai-Ying
Tsai, Yuh-Chyn
Cheng, Ben-Chung
Tsai, Nai-Wen
Lu, Cheng-Hsien
Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title_full Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title_fullStr Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title_full_unstemmed Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title_short Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson’s Disease after Respiratory Muscle Training
title_sort simultaneously improved pulmonary and cardiovascular autonomic function and short-term functional outcomes in patients with parkinson’s disease after respiratory muscle training
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074532/
https://www.ncbi.nlm.nih.gov/pubmed/31979103
http://dx.doi.org/10.3390/jcm9020316
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