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Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up

We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de n...

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Autores principales: Perales, María, Valenzuela, Pedro L., Barakat, Ruben, Cordero, Yaiza, Peláez, Mireia, López, Carmen, Ruilope, Luis M., Santos-Lozano, Alejandro, Lucia, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074577/
https://www.ncbi.nlm.nih.gov/pubmed/32023833
http://dx.doi.org/10.3390/jcm9020379
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author Perales, María
Valenzuela, Pedro L.
Barakat, Ruben
Cordero, Yaiza
Peláez, Mireia
López, Carmen
Ruilope, Luis M.
Santos-Lozano, Alejandro
Lucia, Alejandro
author_facet Perales, María
Valenzuela, Pedro L.
Barakat, Ruben
Cordero, Yaiza
Peláez, Mireia
López, Carmen
Ruilope, Luis M.
Santos-Lozano, Alejandro
Lucia, Alejandro
author_sort Perales, María
collection PubMed
description We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised, moderate-intensity exercise program (three sessions/week)) or control group (n = 660). Maternal outcomes were excessive gestational weight gain (EGWG), gestational hypertension/diabetes and, at follow-up, return to pre-pregnancy weight within six months, hypertension, overweight/obesity, and other cardiometabolic conditions. Offspring outcomes were macrosomia and low-birthweight and, at follow-up, overweight/obesity, low-weight, and cardiometabolic conditions. Adherence to the intervention, which proved safe, was > 95%. Pregnancy exercise reduced the risk of EGWG, gestational hypertension, and diabetes (adjusted odds ratio (OR) and 95% confidence interval: 0.60 (0.46–0.79), 0.39 (0.23–0.67), and 0.48 (0.28–0.84)), and it was associated with a greater likelihood of returning to pre-pregnancy weight (2.37 (1.26–4.54)) and a lower risk of maternal cardiometabolic conditions (0.27 (0.08–0.95)) at the end of follow-up (median 6.1 years (interquartile range 1.8)). Pregnancy exercise also reduced the risk of macrosomia (0.36 (0.20–0.63)) and of childhood overweight/obesity during the first year (0.20 (0.06–0.63)). Our findings suggest that pregnancy exercise might protect maternal/offspring health.
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spelling pubmed-70745772020-03-20 Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up Perales, María Valenzuela, Pedro L. Barakat, Ruben Cordero, Yaiza Peláez, Mireia López, Carmen Ruilope, Luis M. Santos-Lozano, Alejandro Lucia, Alejandro J Clin Med Article We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised, moderate-intensity exercise program (three sessions/week)) or control group (n = 660). Maternal outcomes were excessive gestational weight gain (EGWG), gestational hypertension/diabetes and, at follow-up, return to pre-pregnancy weight within six months, hypertension, overweight/obesity, and other cardiometabolic conditions. Offspring outcomes were macrosomia and low-birthweight and, at follow-up, overweight/obesity, low-weight, and cardiometabolic conditions. Adherence to the intervention, which proved safe, was > 95%. Pregnancy exercise reduced the risk of EGWG, gestational hypertension, and diabetes (adjusted odds ratio (OR) and 95% confidence interval: 0.60 (0.46–0.79), 0.39 (0.23–0.67), and 0.48 (0.28–0.84)), and it was associated with a greater likelihood of returning to pre-pregnancy weight (2.37 (1.26–4.54)) and a lower risk of maternal cardiometabolic conditions (0.27 (0.08–0.95)) at the end of follow-up (median 6.1 years (interquartile range 1.8)). Pregnancy exercise also reduced the risk of macrosomia (0.36 (0.20–0.63)) and of childhood overweight/obesity during the first year (0.20 (0.06–0.63)). Our findings suggest that pregnancy exercise might protect maternal/offspring health. MDPI 2020-01-31 /pmc/articles/PMC7074577/ /pubmed/32023833 http://dx.doi.org/10.3390/jcm9020379 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Perales, María
Valenzuela, Pedro L.
Barakat, Ruben
Cordero, Yaiza
Peláez, Mireia
López, Carmen
Ruilope, Luis M.
Santos-Lozano, Alejandro
Lucia, Alejandro
Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title_full Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title_fullStr Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title_full_unstemmed Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title_short Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
title_sort gestational exercise and maternal and child health: effects until delivery and at post-natal follow-up
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074577/
https://www.ncbi.nlm.nih.gov/pubmed/32023833
http://dx.doi.org/10.3390/jcm9020379
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