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Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up
We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de n...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074577/ https://www.ncbi.nlm.nih.gov/pubmed/32023833 http://dx.doi.org/10.3390/jcm9020379 |
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author | Perales, María Valenzuela, Pedro L. Barakat, Ruben Cordero, Yaiza Peláez, Mireia López, Carmen Ruilope, Luis M. Santos-Lozano, Alejandro Lucia, Alejandro |
author_facet | Perales, María Valenzuela, Pedro L. Barakat, Ruben Cordero, Yaiza Peláez, Mireia López, Carmen Ruilope, Luis M. Santos-Lozano, Alejandro Lucia, Alejandro |
author_sort | Perales, María |
collection | PubMed |
description | We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised, moderate-intensity exercise program (three sessions/week)) or control group (n = 660). Maternal outcomes were excessive gestational weight gain (EGWG), gestational hypertension/diabetes and, at follow-up, return to pre-pregnancy weight within six months, hypertension, overweight/obesity, and other cardiometabolic conditions. Offspring outcomes were macrosomia and low-birthweight and, at follow-up, overweight/obesity, low-weight, and cardiometabolic conditions. Adherence to the intervention, which proved safe, was > 95%. Pregnancy exercise reduced the risk of EGWG, gestational hypertension, and diabetes (adjusted odds ratio (OR) and 95% confidence interval: 0.60 (0.46–0.79), 0.39 (0.23–0.67), and 0.48 (0.28–0.84)), and it was associated with a greater likelihood of returning to pre-pregnancy weight (2.37 (1.26–4.54)) and a lower risk of maternal cardiometabolic conditions (0.27 (0.08–0.95)) at the end of follow-up (median 6.1 years (interquartile range 1.8)). Pregnancy exercise also reduced the risk of macrosomia (0.36 (0.20–0.63)) and of childhood overweight/obesity during the first year (0.20 (0.06–0.63)). Our findings suggest that pregnancy exercise might protect maternal/offspring health. |
format | Online Article Text |
id | pubmed-7074577 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70745772020-03-20 Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up Perales, María Valenzuela, Pedro L. Barakat, Ruben Cordero, Yaiza Peláez, Mireia López, Carmen Ruilope, Luis M. Santos-Lozano, Alejandro Lucia, Alejandro J Clin Med Article We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised, moderate-intensity exercise program (three sessions/week)) or control group (n = 660). Maternal outcomes were excessive gestational weight gain (EGWG), gestational hypertension/diabetes and, at follow-up, return to pre-pregnancy weight within six months, hypertension, overweight/obesity, and other cardiometabolic conditions. Offspring outcomes were macrosomia and low-birthweight and, at follow-up, overweight/obesity, low-weight, and cardiometabolic conditions. Adherence to the intervention, which proved safe, was > 95%. Pregnancy exercise reduced the risk of EGWG, gestational hypertension, and diabetes (adjusted odds ratio (OR) and 95% confidence interval: 0.60 (0.46–0.79), 0.39 (0.23–0.67), and 0.48 (0.28–0.84)), and it was associated with a greater likelihood of returning to pre-pregnancy weight (2.37 (1.26–4.54)) and a lower risk of maternal cardiometabolic conditions (0.27 (0.08–0.95)) at the end of follow-up (median 6.1 years (interquartile range 1.8)). Pregnancy exercise also reduced the risk of macrosomia (0.36 (0.20–0.63)) and of childhood overweight/obesity during the first year (0.20 (0.06–0.63)). Our findings suggest that pregnancy exercise might protect maternal/offspring health. MDPI 2020-01-31 /pmc/articles/PMC7074577/ /pubmed/32023833 http://dx.doi.org/10.3390/jcm9020379 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Perales, María Valenzuela, Pedro L. Barakat, Ruben Cordero, Yaiza Peláez, Mireia López, Carmen Ruilope, Luis M. Santos-Lozano, Alejandro Lucia, Alejandro Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title | Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title_full | Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title_fullStr | Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title_full_unstemmed | Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title_short | Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up |
title_sort | gestational exercise and maternal and child health: effects until delivery and at post-natal follow-up |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074577/ https://www.ncbi.nlm.nih.gov/pubmed/32023833 http://dx.doi.org/10.3390/jcm9020379 |
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