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Air-Bubble Induced Mixing: A Fluidic Mixer Chip
In this study, we report the design and fabrication of a novel fluidic mixer. As proof-of-concept, the laminar flow in the main channel is firstly filled with small air-bubbles, which act as active stirrers inducing chaotic convective turbulent flow, and thus enhance the solutes mixing even at a low...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074661/ https://www.ncbi.nlm.nih.gov/pubmed/32074944 http://dx.doi.org/10.3390/mi11020195 |
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author | Jia, Xiaoyu Che, Bingchen Jing, Guangyin Zhang, Ce |
author_facet | Jia, Xiaoyu Che, Bingchen Jing, Guangyin Zhang, Ce |
author_sort | Jia, Xiaoyu |
collection | PubMed |
description | In this study, we report the design and fabrication of a novel fluidic mixer. As proof-of-concept, the laminar flow in the main channel is firstly filled with small air-bubbles, which act as active stirrers inducing chaotic convective turbulent flow, and thus enhance the solutes mixing even at a low input flow rate. To further increase mixing efficiency, a design of neck constriction is included, which changes the relative positions of the inclusion bubbles significantly. The redistribution of liquid volume among bubbles then causes complex flow profile, which further enhances mixing. This work demonstrates a unique approach of utilizing air bubbles to facilitate mixing in bulk solution, which can find the potential applications in microfluidics, fast medical analysis, and biochemical synthesis. |
format | Online Article Text |
id | pubmed-7074661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70746612020-03-20 Air-Bubble Induced Mixing: A Fluidic Mixer Chip Jia, Xiaoyu Che, Bingchen Jing, Guangyin Zhang, Ce Micromachines (Basel) Communication In this study, we report the design and fabrication of a novel fluidic mixer. As proof-of-concept, the laminar flow in the main channel is firstly filled with small air-bubbles, which act as active stirrers inducing chaotic convective turbulent flow, and thus enhance the solutes mixing even at a low input flow rate. To further increase mixing efficiency, a design of neck constriction is included, which changes the relative positions of the inclusion bubbles significantly. The redistribution of liquid volume among bubbles then causes complex flow profile, which further enhances mixing. This work demonstrates a unique approach of utilizing air bubbles to facilitate mixing in bulk solution, which can find the potential applications in microfluidics, fast medical analysis, and biochemical synthesis. MDPI 2020-02-14 /pmc/articles/PMC7074661/ /pubmed/32074944 http://dx.doi.org/10.3390/mi11020195 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Jia, Xiaoyu Che, Bingchen Jing, Guangyin Zhang, Ce Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title | Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title_full | Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title_fullStr | Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title_full_unstemmed | Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title_short | Air-Bubble Induced Mixing: A Fluidic Mixer Chip |
title_sort | air-bubble induced mixing: a fluidic mixer chip |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074661/ https://www.ncbi.nlm.nih.gov/pubmed/32074944 http://dx.doi.org/10.3390/mi11020195 |
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