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Impact of the Activation Status of the Akt/mTOR Signalling Pathway on the Clinical Behaviour of Synovial Sarcoma: Retrospective Analysis of 174 Patients at a Single Institution
PURPOSE: Phosphoinositide 3-kinase (PI3K) and the downstream Akt/mammalian target of rapamycin (mTOR) pathway are central to the control of cell proliferation and survival. Although abnormal activation of this pathway has been well established in a variety of tumours, limited studies are available o...
Autores principales: | Li, Ying-Xue, Ding, Shan-Shan, Wen, Wen-Juan, Han, Lin, Wang, Hong-Qun, Shi, Huai-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074818/ https://www.ncbi.nlm.nih.gov/pubmed/32210617 http://dx.doi.org/10.2147/CMAR.S228578 |
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