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AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges

The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research co...

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Detalles Bibliográficos
Autores principales: Hoinka, Jan, Wang, Yijie, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074893/
https://www.ncbi.nlm.nih.gov/pubmed/32160038
http://dx.doi.org/10.1089/cmb.2019.0470
Descripción
Sumario:The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research community at large makes this software a highly effective tool for accelerating the design and development of novel oligonucleotide-based drugs and other biotechnologies.