AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges

The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research co...

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Detalles Bibliográficos
Autores principales: Hoinka, Jan, Wang, Yijie, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074893/
https://www.ncbi.nlm.nih.gov/pubmed/32160038
http://dx.doi.org/10.1089/cmb.2019.0470
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author Hoinka, Jan
Wang, Yijie
Przytycka, Teresa M.
author_facet Hoinka, Jan
Wang, Yijie
Przytycka, Teresa M.
author_sort Hoinka, Jan
collection PubMed
description The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research community at large makes this software a highly effective tool for accelerating the design and development of novel oligonucleotide-based drugs and other biotechnologies.
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spelling pubmed-70748932020-03-16 AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges Hoinka, Jan Wang, Yijie Przytycka, Teresa M. J Comput Biol Research Articles The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research community at large makes this software a highly effective tool for accelerating the design and development of novel oligonucleotide-based drugs and other biotechnologies. Mary Ann Liebert, Inc., publishers 2020-03-01 2020-03-11 /pmc/articles/PMC7074893/ /pubmed/32160038 http://dx.doi.org/10.1089/cmb.2019.0470 Text en © Jan Hoinka, et al., 2020. Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research Articles
Hoinka, Jan
Wang, Yijie
Przytycka, Teresa M.
AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title_full AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title_fullStr AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title_full_unstemmed AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title_short AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
title_sort aptablocks online: a web-based toolkit for the in silico design of oligonucleotide sticky bridges
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074893/
https://www.ncbi.nlm.nih.gov/pubmed/32160038
http://dx.doi.org/10.1089/cmb.2019.0470
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