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DTD: An R Package for Digital Tissue Deconvolution

Digital tissue deconvolution (DTD) estimates the cellular composition of a tissue from its bulk gene-expression profile. For this, DTD approximates the bulk as a mixture of cell-specific expression profiles. Different tissues have different cellular compositions, with cells in different activation s...

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Detalles Bibliográficos
Autores principales: Schön, Marian, Simeth, Jakob, Heinrich, Paul, Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Altenbuchinger, Michael, Spang, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074920/
https://www.ncbi.nlm.nih.gov/pubmed/31995409
http://dx.doi.org/10.1089/cmb.2019.0469

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