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Fanconi anemia pathway as a prospective target for cancer intervention

Fanconi anemia (FA) is a recessive genetic disorder caused by biallelic mutations in at least one of 22 FA genes. Beyond its pathological presentation of bone marrow failure and congenital abnormalities, FA is associated with chromosomal abnormality and genomic instability, and thus represents a gen...

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Detalles Bibliográficos
Autores principales: Liu, Wenjun, Palovcak, Anna, Li, Fang, Zafar, Alyan, Yuan, Fenghua, Zhang, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075017/
https://www.ncbi.nlm.nih.gov/pubmed/32190289
http://dx.doi.org/10.1186/s13578-020-00401-7