Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells

Gonadotropin-releasing hormone (GnRH) neurons provide a fundamental signal for the onset of puberty and subsequent reproductive functions by secretion of gonadotropin-releasing hormone. Their disrupted development or function leads to congenital hypogonadotropic hypogonadism (CHH). To model the deve...

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Detalles Bibliográficos
Autores principales: Lund, Carina, Yellapragada, Venkatram, Vuoristo, Sanna, Balboa, Diego, Trova, Sara, Allet, Cecile, Eskici, Nazli, Pulli, Kristiina, Giacobini, Paolo, Tuuri, Timo, Raivio, Taneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075073/
https://www.ncbi.nlm.nih.gov/pubmed/31996360
http://dx.doi.org/10.1242/dmm.040105

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