Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells

Drug-loaded, PEGylated, organic-modified silica (ORMOSIL) nanoparticles prepared by microemulsion condensation of vinyltriethoxysilane (VTES) were investigated as potential nanovectors for cancer therapy. To target cancer stem cells, anti-CD44v6 antibody and hyaluronic acid (HA) were conjugated to a...

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Detalles Bibliográficos
Autores principales: Morillas-Becerril, Lucía, Peta, Elektra, Gabrielli, Luca, Russo, Venera, Lubian, Elisa, Nodari, Luca, Ferlin, Maria Grazia, Scrimin, Paolo, Palù, Giorgio, Barzon, Luisa, Castagliuolo, Ignazio, Mancin, Fabrizio, Trevisan, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075197/
https://www.ncbi.nlm.nih.gov/pubmed/32050605
http://dx.doi.org/10.3390/nano10020298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075197/
https://www.ncbi.nlm.nih.gov/pubmed/32050605
http://dx.doi.org/10.3390/nano10020298

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