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Hexamer phasing governs transcription initiation in the 3′-leader of Ebola virus

The genomic, bipartite replication promoter of Ebola virus (EBOV) consists of elements 1 (PE1) and 2 (PE2). PE1 (55 nt at the 3′-terminus) is separated from PE2 (harboring eight 3′-UN(5) hexamers) by the transcription start sequence (TSS) of the first nucleoprotein (NP) gene plus a spacer sequence....

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Detalles Bibliográficos
Autores principales: Bach, Simone, Biedenkopf, Nadine, Grünweller, Arnold, Becker, Stephan, Hartmann, Roland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075260/
https://www.ncbi.nlm.nih.gov/pubmed/31924730
http://dx.doi.org/10.1261/rna.073718.119

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