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The impact of the field width on VMAT plan quality and the assessment of half field method

PURPOSE: The goal of this work is to investigate the field width dependence of the volumetric modulated arc therapy (VMAT) plan quality and to propose a half field method to irradiate large volumes effectively with VMAT. MATERIALS AND METHODS: We compared four different VMAT methods; namely three fu...

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Detalles Bibliográficos
Autores principales: Ugurlu, Berat Tugrul, Temelli, Oztun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075377/
https://www.ncbi.nlm.nih.gov/pubmed/32077576
http://dx.doi.org/10.1002/acm2.12834
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author Ugurlu, Berat Tugrul
Temelli, Oztun
author_facet Ugurlu, Berat Tugrul
Temelli, Oztun
author_sort Ugurlu, Berat Tugrul
collection PubMed
description PURPOSE: The goal of this work is to investigate the field width dependence of the volumetric modulated arc therapy (VMAT) plan quality and to propose a half field method to irradiate large volumes effectively with VMAT. MATERIALS AND METHODS: We compared four different VMAT methods; namely three full field (3ff), four full field (4ff), three half field (3hf), four half field (4hf). To evaluate the impact of the field width on VMAT plan quality, 12 different size PTVs were created in the virtual phantom and treatment plans generated for each PTV were compared. The effectiveness of our half field method was tested using computed tomography (CT) data of 10 nasopharyngeal carcinoma patients. RESULTS: In the virtual phantom study, organs at risk (OAR) mean dose, the maximum point dose, and Homogeneity Index (HI) were found to be field width dependent. Conformation Number (CN) was not significantly affected. In the clinical study, 4hf plans obtained statistically significant dose reduction at brainstem (P < 0.001), right parotid (P = 0.034), oral cavity (P < 0.001), larynx (P = 0.003), cochlea (P = 0.017), lips (P = 0.024), and Body‐PTV (P = 0.04) compared to 4ff plans. CONCLUSION: Our results indicate that VMAT plan quality is dependent on the field width. Half field VMAT method, with the help of reduced field width, shows a clear advantage for the irradiation of large size targets compared to traditionally used full field VMAT plans.
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spelling pubmed-70753772020-03-17 The impact of the field width on VMAT plan quality and the assessment of half field method Ugurlu, Berat Tugrul Temelli, Oztun J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: The goal of this work is to investigate the field width dependence of the volumetric modulated arc therapy (VMAT) plan quality and to propose a half field method to irradiate large volumes effectively with VMAT. MATERIALS AND METHODS: We compared four different VMAT methods; namely three full field (3ff), four full field (4ff), three half field (3hf), four half field (4hf). To evaluate the impact of the field width on VMAT plan quality, 12 different size PTVs were created in the virtual phantom and treatment plans generated for each PTV were compared. The effectiveness of our half field method was tested using computed tomography (CT) data of 10 nasopharyngeal carcinoma patients. RESULTS: In the virtual phantom study, organs at risk (OAR) mean dose, the maximum point dose, and Homogeneity Index (HI) were found to be field width dependent. Conformation Number (CN) was not significantly affected. In the clinical study, 4hf plans obtained statistically significant dose reduction at brainstem (P < 0.001), right parotid (P = 0.034), oral cavity (P < 0.001), larynx (P = 0.003), cochlea (P = 0.017), lips (P = 0.024), and Body‐PTV (P = 0.04) compared to 4ff plans. CONCLUSION: Our results indicate that VMAT plan quality is dependent on the field width. Half field VMAT method, with the help of reduced field width, shows a clear advantage for the irradiation of large size targets compared to traditionally used full field VMAT plans. John Wiley and Sons Inc. 2020-02-20 /pmc/articles/PMC7075377/ /pubmed/32077576 http://dx.doi.org/10.1002/acm2.12834 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ugurlu, Berat Tugrul
Temelli, Oztun
The impact of the field width on VMAT plan quality and the assessment of half field method
title The impact of the field width on VMAT plan quality and the assessment of half field method
title_full The impact of the field width on VMAT plan quality and the assessment of half field method
title_fullStr The impact of the field width on VMAT plan quality and the assessment of half field method
title_full_unstemmed The impact of the field width on VMAT plan quality and the assessment of half field method
title_short The impact of the field width on VMAT plan quality and the assessment of half field method
title_sort impact of the field width on vmat plan quality and the assessment of half field method
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075377/
https://www.ncbi.nlm.nih.gov/pubmed/32077576
http://dx.doi.org/10.1002/acm2.12834
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