Cargando…

Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4

Background: Integrity of functional brain networks is closely associated with maintained cognitive performance at old age. Consistently, both carrier status of Apolipoprotein E ε4 allele (APOE4), and age-related aggregation of Alzheimer’s disease (AD) pathology result in altered brain network connec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quevenco, Frances C., van Bergen, Jiri M., Treyer, Valerie, Studer, Sandro T., Kagerer, Sonja M., Meyer, Rafael, Gietl, Anton F., Kaufmann, Philipp A., Nitsch, Roger M., Hock, Christoph, Unschuld, Paul G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075450/ https://www.ncbi.nlm.nih.gov/pubmed/32210782 http://dx.doi.org/10.3389/fnagi.2020.00046

Ejemplares similares

APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults
por: Kagerer, Sonja M., et al.
Publicado: (2020)

Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience–a study in exceptional aging
por: Treyer, Valerie, et al.
Publicado: (2021)

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment
por: van Bergen, J. M. G., et al.
Publicado: (2016)

Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age
por: Kagerer, Sonja M., et al.
Publicado: (2022)

Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women
por: Bachmann, Dario, et al.
Publicado: (2022)

GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults
por: Quevenco, F.C., et al.
Publicado: (2019)

Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment
por: Michels, Lars, et al.
Publicado: (2017)

Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System
por: Steininger, Stefanie C., et al.
Publicado: (2014)

Age-, sex-, and pathology-related variability in brain structure and cognition
por: Bachmann, Dario, et al.
Publicado: (2023)

Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia
por: Treyer, Valerie, et al.
Publicado: (2020)

Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects
por: Schreiner, Simon J., et al.
Publicado: (2014)

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer’s disease
por: Quevenco, Frances C., et al.
Publicado: (2017)

Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly
por: Zhang, Junhao, et al.
Publicado: (2023)

Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography
por: Laurig, Mathias, et al.
Publicado: (2013)

Brain areas with normatively greater cerebral perfusion in early life may be more susceptible to beta amyloid deposition in late life
por: Meier, Irene B., et al.
Publicado: (2020)

EEG-fMRI Signal Coupling Is Modulated in Subjects With Mild Cognitive Impairment and Amyloid Deposition
por: Michels, Lars, et al.
Publicado: (2021)

ATN profile classification across two independent prospective cohorts
por: Peretti, Débora E., et al.
Publicado: (2023)

APOEε4 potentiates the relationship between amyloid-β and tau pathologies
por: Therriault, Joseph, et al.
Publicado: (2020)

Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients
por: Kälin, Andrea M., et al.
Publicado: (2017)

Intraindividual variability across cognitive tasks as a potential marker for prodromal Alzheimer’s disease
por: Kälin, Andrea M., et al.
Publicado: (2014)

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
por: Baek, Min Seok, et al.
Publicado: (2020)

Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction
por: Düzel, Emrah, et al.
Publicado: (2022)

Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults
por: Pereira, Joana B., et al.
Publicado: (2020)

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau
por: Kang, Silvia S., et al.
Publicado: (2018)

Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer’s disease
por: Sadleir, Katherine R., et al.
Publicado: (2023)

Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer’s disease-related microvascular cerebral amyloid angiopathy
por: Merlini, Mario, et al.
Publicado: (2016)

The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer’s disease
por: Bonham, Luke W., et al.
Publicado: (2016)

Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals
por: Hong, Yun Jeong, et al.
Publicado: (2022)

Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia
por: Salvadó, Gemma, et al.
Publicado: (2021)

Tauvid™: The First FDA-Approved PET Tracer for Imaging Tau Pathology in Alzheimer’s Disease
por: Jie, Caitlin V. M. L., et al.
Publicado: (2021)

Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau
por: Mattsson‐Carlgren, Niklas, et al.
Publicado: (2021)

Astrocytic function is associated with both amyloid-β and tau pathology in non-demented APOE ϵ4 carriers
por: Spotorno, Nicola, et al.
Publicado: (2022)

Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
por: Camacho, Jessica, et al.
Publicado: (2019)

APOE-amyloid interaction: Therapeutic targets
por: Wisniewski, Thomas, et al.
Publicado: (2020)

Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity
por: Pereira, Joana B, et al.
Publicado: (2019)

The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation
por: Nelson, Maxine R., et al.
Publicado: (2023)

APOE effects on regional tau in preclinical Alzheimer’s disease
por: Young, Christina B., et al.
Publicado: (2023)

ApoE Alzheimer’s Disease Aβ-amyloid plaque morphology varies according to APOE isotype
por: Caesar, Ina, et al.
Publicado: (2023)

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system
por: Tackenberg, Christian, et al.
Publicado: (2020)

Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas
por: den Haan, Jurre, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1rf8e7nk1irpnjss9gpd540r0t