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Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences

SUMMARY: Antibody repertoires reveal insights into the biology of the adaptive immune system and empower diagnostics and therapeutics. There are currently multiple tools available for the annotation of antibody sequences. All downstream analyses such as choosing lead drug candidates depend on the co...

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Detalles Bibliográficos
Autores principales: Smakaj, Erand, Babrak, Lmar, Ohlin, Mats, Shugay, Mikhail, Briney, Bryan, Tosoni, Deniz, Galli, Christopher, Grobelsek, Vendi, D’Angelo, Igor, Olson, Branden, Reddy, Sai, Greiff, Victor, Trück, Johannes, Marquez, Susanna, Lees, William, Miho, Enkelejda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075533/
https://www.ncbi.nlm.nih.gov/pubmed/31873728
http://dx.doi.org/10.1093/bioinformatics/btz845

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