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Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy

We present a systematic characterization of the optical properties (µ(a) and µ(s)’) of nine representative ex vivo porcine tissues over a broadband spectrum (650-1100 nm). We applied time-resolved diffuse optical spectroscopy measurements for recovering the optical properties of porcine tissues depi...

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Autores principales: Mosca, Sara, Lanka, Pranav, Stone, Nick, Konugolu Venkata Sekar, Sanathana, Matousek, Pavel, Valentini, Gianluca, Pifferi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075607/
https://www.ncbi.nlm.nih.gov/pubmed/32206436
http://dx.doi.org/10.1364/BOE.386349
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author Mosca, Sara
Lanka, Pranav
Stone, Nick
Konugolu Venkata Sekar, Sanathana
Matousek, Pavel
Valentini, Gianluca
Pifferi, Antonio
author_facet Mosca, Sara
Lanka, Pranav
Stone, Nick
Konugolu Venkata Sekar, Sanathana
Matousek, Pavel
Valentini, Gianluca
Pifferi, Antonio
author_sort Mosca, Sara
collection PubMed
description We present a systematic characterization of the optical properties (µ(a) and µ(s)’) of nine representative ex vivo porcine tissues over a broadband spectrum (650-1100 nm). We applied time-resolved diffuse optical spectroscopy measurements for recovering the optical properties of porcine tissues depicting a realistic representation of the tissue heterogeneity and morphology likely to be found in different ex vivo tissues. The results demonstrate a large spectral and inter-tissue variation of optical properties. The data can be exploited for planning or simulating ex vivo experiments with various biophotonics techniques, or even to construct artificial structures mimicking specific pathologies exploiting the wide assortment in optical properties.
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spelling pubmed-70756072020-03-23 Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy Mosca, Sara Lanka, Pranav Stone, Nick Konugolu Venkata Sekar, Sanathana Matousek, Pavel Valentini, Gianluca Pifferi, Antonio Biomed Opt Express Article We present a systematic characterization of the optical properties (µ(a) and µ(s)’) of nine representative ex vivo porcine tissues over a broadband spectrum (650-1100 nm). We applied time-resolved diffuse optical spectroscopy measurements for recovering the optical properties of porcine tissues depicting a realistic representation of the tissue heterogeneity and morphology likely to be found in different ex vivo tissues. The results demonstrate a large spectral and inter-tissue variation of optical properties. The data can be exploited for planning or simulating ex vivo experiments with various biophotonics techniques, or even to construct artificial structures mimicking specific pathologies exploiting the wide assortment in optical properties. Optical Society of America 2020-02-28 /pmc/articles/PMC7075607/ /pubmed/32206436 http://dx.doi.org/10.1364/BOE.386349 Text en Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) . Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.
spellingShingle Article
Mosca, Sara
Lanka, Pranav
Stone, Nick
Konugolu Venkata Sekar, Sanathana
Matousek, Pavel
Valentini, Gianluca
Pifferi, Antonio
Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title_full Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title_fullStr Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title_full_unstemmed Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title_short Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
title_sort optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075607/
https://www.ncbi.nlm.nih.gov/pubmed/32206436
http://dx.doi.org/10.1364/BOE.386349
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