BMD42-2910, a Novel Benzoxazole Derivative, Shows a Potent Anti-prion Activity and Prolongs the Mean Survival in an Animal Model of Prion Disease

Prion diseases are a group of neurodegenerative and fatal central nervous system disorders. The pathogenic mechanism involves the conversion of cellular prion protein (PrP(C)) to an altered scrapie isoform (PrP(Sc)), which accumulates in amyloid deposits in the brain. However, no therapeutic drugs h...

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Detalles Bibliográficos
Autores principales: Hyeon, Jae Wook, Noh, Ran, Choi, Jiwon, Lee, Sol Moe, Lee, Yeong Seon, An, Seong Soo A., No, Kyoung Tai, Lee, Jeongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075655/
https://www.ncbi.nlm.nih.gov/pubmed/32122111
http://dx.doi.org/10.5607/en.2020.29.1.93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075655/
https://www.ncbi.nlm.nih.gov/pubmed/32122111
http://dx.doi.org/10.5607/en.2020.29.1.93

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