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The role of TP53 gain-of-function mutation in multifocal glioblastoma

PURPOSE: The phenotypic and genotypic landscapes in multifocal glioblastoma (MF GBM) cases can vary greatly among lesions. In a MF GBM patient, the rapid development of a secondary lesion was investigated to determine if a unique genetic signature could account for the apparent increased malignancy...

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Detalles Bibliográficos
Autores principales: Olafson, Lauren R., Gunawardena, Manuri, Nixdorf, Sheri, McDonald, Kerrie L., Rapkins, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075848/
https://www.ncbi.nlm.nih.gov/pubmed/32002804
http://dx.doi.org/10.1007/s11060-019-03318-5

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