Prolyl hydroxylase 2 silencing enhances the paracrine effects of mesenchymal stem cells on necrotizing enterocolitis in an NF-κB-dependent mechanism

Treatment options for necrotizing enterocolitis (NEC) remain inadequate. Here we examined if and how prolyl hydroxylase 2 (PHD2) silencing enhances the paracrine effects of bone-marrow-derived mesenchymal stem cells (BM-MSCs) on NEC. In this study, BM-MSCs were transduced with lentiviruses containin...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Zhang, Haifeng, Zheng, Yue, Min, Xiaohui, Luo, Yujun, Zhou, Weijie, Ma, Faxin, Li, Jinliang, Lu, Quan, Zhang, Chen, Cai, Huihua, Sha, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075868/
https://www.ncbi.nlm.nih.gov/pubmed/32179740
http://dx.doi.org/10.1038/s41419-020-2378-3

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