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Tethered primary hepatocyte spheroids on polystyrene multi-well plates for high-throughput drug safety testing
Hepatocyte spheroids are useful models for mimicking liver phenotypes in vitro because of their three-dimensionality. However, the lack of a biomaterial platform which allows the facile manipulation of spheroid cultures on a large scale severely limits their application in automated high-throughput...
Autores principales: | Tasnim, Farah, Singh, Nisha Hari, Tan, Elijah Keng Foo, Xing, Jiangwa, Li, Huan, Hissette, Sebastien, Manesh, Sravanthy, Fulwood, Justina, Gupta, Kapish, Ng, Chan Way, Xu, Shuoyu, Hill, Jeffrey, Yu, Hanry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075904/ https://www.ncbi.nlm.nih.gov/pubmed/32179810 http://dx.doi.org/10.1038/s41598-020-61699-4 |
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