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PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response
Pancreatic ductal adenocarcinoma (PDAC) is associated with metaplastic changes in the pancreas but the transcriptional program underlying these changes is incompletely understood. The zinc finger transcription factor, PRDM3, is lowly expressed in normal pancreatic acini and its expression increases...
Autores principales: | Ye, Jie, Huang, Anpei, Wang, Haitao, Zhang, Anni M. Y., Huang, Xiaojun, Lan, Qingping, Sato, Tomohiko, Goyama, Susumu, Kurokawa, Mineo, Deng, Chuxia, Sander, Maike, Schaeffer, David F., Li, Wen, Kopp, Janel L., Xie, Ruiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075911/ https://www.ncbi.nlm.nih.gov/pubmed/32179733 http://dx.doi.org/10.1038/s41419-020-2371-x |
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