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The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice
The SUSD4 (Sushi domain-containing protein 4) gene encodes a complement inhibitor that is frequently deleted in 1q41q42 microdeletion syndrome, a multisystem congenital disorder that includes neurodevelopmental abnormalities. To understand SUSD4's role in the mammalian nervous system, we analyz...
Autores principales: | Zhu, Hongling, Meissner, Laura E., Byrnes, Colleen, Tuymetova, Galina, Tifft, Cynthia J., Proia, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075988/ https://www.ncbi.nlm.nih.gov/pubmed/32179479 http://dx.doi.org/10.1016/j.isci.2020.100957 |
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