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microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development

Aberrant epigenetic modification, including N(6)-methylation of adenosine (m6A), has been frequently reported in embryos derived from parthenogenetic activation (PA). However, the role of Igf2bp1 expression pattern in m6A modification and the mechanism through which Igf2bp1 function is regulated in...

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Detalles Bibliográficos
Autores principales: Hao, Jindong, Hu, Haobo, Jiang, Ziping, Yu, Xianfeng, Li, Chengshun, Chen, Lin, Xia, Yidan, Liu, Da, Wang, Dongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076016/
https://www.ncbi.nlm.nih.gov/pubmed/32179813
http://dx.doi.org/10.1038/s41598-020-61816-3