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microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development
Aberrant epigenetic modification, including N(6)-methylation of adenosine (m6A), has been frequently reported in embryos derived from parthenogenetic activation (PA). However, the role of Igf2bp1 expression pattern in m6A modification and the mechanism through which Igf2bp1 function is regulated in...
Autores principales: | Hao, Jindong, Hu, Haobo, Jiang, Ziping, Yu, Xianfeng, Li, Chengshun, Chen, Lin, Xia, Yidan, Liu, Da, Wang, Dongxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076016/ https://www.ncbi.nlm.nih.gov/pubmed/32179813 http://dx.doi.org/10.1038/s41598-020-61816-3 |
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