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A unique DNA-binding mode of African swine fever virus AP endonuclease

African swine fever virus (ASFV) is highly contagious and can cause lethal disease in pigs. ASFV is primarily replicated in the cytoplasm of pig macrophages, which is oxidative and caused constant damage to ASFV genome. ASFV AP endonuclease (AsfvAP) catalyzes DNA cleavage reaction at the abasic site...

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Detalles Bibliográficos
Autores principales:	Chen, Yiqing, Chen, Xi, Huang, Qi, Shao, Zhiwei, Gao, Yanqing, Li, Yangyang, Yang, Chun, Liu, Hehua, Li, Jixi, Wang, Qiyao, Ma, Jinbiao, Zhang, Yong-Zhen, Gu, Yijun, Gan, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076025/ https://www.ncbi.nlm.nih.gov/pubmed/32194979 http://dx.doi.org/10.1038/s41421-020-0146-2

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