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Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter
Mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) confer resistance to several antimalarial drugs such as chloroquine (CQ) or piperaquine (PPQ), a partner molecule in current artemisinin-based combination therapies. As a member of the Drug/Metabolite Transporter (DMT)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076037/ https://www.ncbi.nlm.nih.gov/pubmed/32179795 http://dx.doi.org/10.1038/s41598-020-61181-1 |