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Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

Mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) confer resistance to several antimalarial drugs such as chloroquine (CQ) or piperaquine (PPQ), a partner molecule in current artemisinin-based combination therapies. As a member of the Drug/Metabolite Transporter (DMT)...

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Detalles Bibliográficos
Autores principales:	Coppée, Romain, Sabbagh, Audrey, Clain, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076037/ https://www.ncbi.nlm.nih.gov/pubmed/32179795 http://dx.doi.org/10.1038/s41598-020-61181-1

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