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Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart

L-arginine:glycine amidinotransferase (AGAT) and its metabolites creatine and homoarginine (HA) have been linked to cardiovascular pathologies in both human and murine studies, but the underlying molecular mechanisms are poorly understood. Here, we report the first analysis of heart transcriptome va...

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Detalles Bibliográficos
Autores principales: Jensen, Märit, Müller, Christian, Choe, Chi-un, Schwedhelm, Edzard, Zeller, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076046/
https://www.ncbi.nlm.nih.gov/pubmed/32179820
http://dx.doi.org/10.1038/s41598-020-61638-3

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